1. Biotechnology Careers: High-Tech, High-Wage Jobs Career Pathways & Training in Northern California

2. What is Biotechnology? The use of living organisms, or parts thereof, to provide useful products, processes and services. Cells are the basic building blocks of living organisms Scientists in the field of biotechnology modify cellular DNA in order to produce useful proteins & other molecules Transcription & Translation DNAProtein

3. Agricultural Biotechnology ► Enhanced pest and disease resistance ► Decrease use of chemicals on farmland ► Enhanced vitamins, micronutrients, etc. ► Increased stress tolerance: drought, salinity, cold, etc. ► “Pharming” to make vaccines and therapeutics. ► Use of cellulosic biomass for biofuels GMOs are feared by some…there is no scientific evidence to support such fears

4. Industrial Biotechnology ► ► Enzymes needed for:   Cheese   Bread   Detergents   Textiles ► Therapeutic molecules to treat human diseases & disorders  Human Growth Factor  Insulin  Other pharmaceuticals ► Antibodies used in:  Vaccines  Disease treatment*  Medical Diagnostics  Cell Identification  Biosensors* Useful proteins or biomolecules produced on an industrial scale by modifying, adding or deleting genetic information (DNA) in an organism, followed by large scale fermentation and biomolecule collection

5. Bioengineering & Biomedical Applications ► DNA & Protein biochips  Medical diagnostics  Basic Genomics Research ► Nanobiotechnology  Biomaterials, such as quantum dots ► Biophotonics ► Biosensors ► Biomedical Engineering  Tissue Engineering  In-vivo Imaging  Robotics

6. Genomics, Proteomics & Bioinformatics Many Human Diseases are Associated with Single Base Changes in the Human Genome: ► Sickle cell anemia ► Hypercholesterolemia ► Cystic fibrosis ► Congenital heart defects ► Obsessive-compulsive disorder ► Marfan syndrome www.hapmap.org “The HapMap is a catalog of common genetic variants that occur in human beings.” Current Study Populations are from: ► Ibadan, Nigeria ► Tokyo, Japan ► Beijing, China ► United States (northern & western European ancestry)

7. Environmental Biotechnology ► Biofuels  New $25 million collaborative research partnership with Chevron ► Cellulytic enzymes ► GMO feedstocks for easier processing ► ► Bioenergy ► ► Bioremediation ► ► Biomass conversion

8. Stem Cells & Tissue Engineering ► October 2005, NIH awarded UC Davis a $6 million grant to launch the Center of Excellence in Translational Human Stem Cell Research ► Director, Dr. Alice Tarantal ► It is one of two centers in the nation! ► Three major research projects:  Increase umbilical cord blood stem cells available for cell transplants  Cell therapy for urinary tract obstruction in children with kidney disease  improve cell imaging that could be used for tracking transplanted stem cells in clinical studies http://www.surgery. wisc.edu/transplant/ research/odoricolab/ stemcellpics.shtml Stem Cells

9. Biotech was born in N. California! The Interstate-80 corridor between the Bay Area and Sacramento is home to a high concentration of biotech companies http://www.bio-link.org/centersCAN.htm We need a highly skilled regional workforce to maintain our preeminence in biotechnology and compete in the global marketplace!

10. Early Training for Careers in Biotechnology Early Training for Careers in Biotechnology ► Take “College Prep” High School Courses:  Science Classes (Biology, Chemistry, Physiology, etc…) with hands-on laboratory training  Math Classes (Algebra, Geometry, Calculus, etc…)  Computer Classes  English Classes In High School, build the skills needed to:  Work effectively as the member of a team  Precisely handle lab equipment and gather data  Carefully analyze and solve problems, based on known facts or data  Clearly communicate the results of your work (written and verbal)

11. Education & Training for a Career in the Life Science Industry High School Diploma Community College Certificate Community College AS Degree Bachelor’s of Science (BS) Degree Master’s of Science (MS) Degree Doctoral Degree (PhD) Laboratory Technician ~$35-40,000/yr Research Scientist ~$50-70,000/yr Laboratory Director ~$65-100,000+/yr Biotech Company CEO ~$100,000+/yr More years of experience ~5yrs ~2yrs ~4-5yrs ~5yrs * * * 1-2yrs ~2yrs

12. Education & Training for a Career in Life Science Academia High School Diploma Community College Certificate Community College AS Degree Bachelor’s of Science (BS) Degree Master’s of Science (MS) Degree Doctoral Degree (PhD) Laboratory Technician ~$35-45,000/yr Research Scientist ~$50-70,000/yr University Professor/Administrator ~$50-100,000+/yr Post-doctoral Researcher (temporary) ~$40-50,000+/yr ~5yrs ~2yrs ~4-5yrs ~5yrs 1-2yrs ~2yrs Adjunct Faculty (temporary) ~$40-50,000+/yr Community College Professor/Administrator ~$50-100,000+/yr K-12 Teacher ~$45-70,000/yr K-12 Credential ~2yrs

13. 2-Year Biotech Training Programs in the Greater Sacramento Region ► American River College / North Valley & Mountain Biotech Center  Biotech Certificate  Biotech Degree (AS) ► http://www.arc.losrios.edu/catalog/Biology.pdf ► Solano Community College  Applied Biotech Certificate  Industrial Biotech Certificate  Industrial Biotech Degree (AS) ► http://www.solano.edu/degrees/catalog_200708/biotech.pdf

14. 4-Year & Graduate Training Programs in the Greater Sacramento Region ► CSU Sacramento  BS, MS in Biological Sciences (various majors) ► http://www.csus.edu/bios/ ► UC Davis  BA/BS in Biological Sciences (various majors) ► http://admissions.ucdavis.edu/academics/major_view.cfm?major=bbis  BS in Biotechnology ► http://admissions.ucdavis.edu/academics/major_view.cfm?major=abit  MS/PhD in Biological Sciences (various majors) ► http://www.dbs.ucdavis.edu/grad/index.html  Designated Emphasis in Biotechnology (for PhD students) ► http://www.biotech.ucdavis.edu/ Note: There are other state (UC, CSU, private) and national universities offering similar programs

15. Thriving Biotech-Related Life Science Job Markets Research Patent Law Administration Teaching Government Regulatory Affairs Health Care Sales & Marketing Technical Writing

16. Average Life Science Salaries (2004) ► College/University Department Head (11/12 month appt.- tenured) $149,250 ► Research Vice President/Director $145,000 ► President/Managing Director (with financial interest in firm) $128,000 ► Professor (11/12 month appointment - tenured) $121,000 ► Laboratory Director $96,600 ► Intermediate Researcher $50,335 ► Secondary School Teacher $43,536 ► College Instructor (9/10 month appt.) $43,000 ► Intermediate Research Technician $33,943 (BS degree) Nationwide, the median income of those in the life sciences is ~$66,480. Data from “Compensation of Life Scientists in the U.S. – 2004” Note: 2007 Salaries in California are ~5-15% higher

17. Local Careers in Biotech Industry The Greater Sacramento Region is poised to become a mixed biotech/life science cluster. Over 100,000 Jobs! per EDD ~100 Life Sciences companies exist along the I-80 Corridor

18. Life Science Companies in the Greater Sacramento Valley* Life Science Companies in the Greater Sacramento Valley* ► Affymetrix ► AgraQuest ► Alza ► Antibodies, Inc. ► Arcadia Biociences ► BioRad ► Dade Microscan ► Davis Sequencing ► Genentech ► Glycometrix (seed stage) ► Hygieia Labs ► IDEXX Labs ► Jackson Labs ► Lipomics Technologies ► Mesolytics (seed stage) ► Miltenyi Biotech ► MMI Genomics ► Monsanto, Calgene campus ► Novozymes ► Novartis ► Pediatric Biosciences (seed stage) ► Pioneer Hibred ► Seminis Seeds ► Synthia LLC (seed stage) ► Thermogenesis ► Telomolecular ► Ventria Biosciences ► Volcano ► Vitalea (seed stage) (*not complete list)

19. ► ► Career Voyages Career Voyages   A career information website hosted by the US Department of Education and the US Department of Labor. ► ► Biotech Work Portal Biotech Work Portal   A comprehensive website with links to information on biotech careers, educational programs, job postings, labor market data and much more! ► ► BiotechEmployment.com BiotechEmployment.com   A survey and salary information database providing annual data on average salaries in the biotech industry. ► ► OneScience.com OneScience.com   A popular job search website for the life science industry. ► ► California Employment Development Department California Employment Development Department   Data on California biotech jobs and industry growth. Online Resources for Biotech Careers

20. http://www.labormarketinfo.edd.ca.gov/cgi/career/?PAGEID=3&SUBID=136 The California Employment Development Department (EDD) Records Data on Biotech Jobs in the State

21. “Soft Skills” are Critical for Career Success ► Your academic qualifications might get you an interview, but to get and keep a job in biotechnology, you need these “soft skills”: Before the interview-  Resume (easy to read, accurate, concise, personal)  Cover letter (perfect grammar/spelling, expresses your desire for the job, elaborates on your personal qualifications and life experiences that make you the “best” candidate)  Phone and email etiquette During the interview-  Firm handshake  Good manners  Appropriate attire  Clear communicator On the job- Team playerTeam player Clear communicatorClear communicator Critical thinkerCritical thinker Ethical, reliable & responsibleEthical, reliable & responsible Follows protocols/directionsFollows protocols/directions

22. What Path Should You Follow? ► Predictions of Aggressive Job Growth in:  Health Sciences  Biotechnology & Bioinformatics  Computer and Information Science ► All of these careers require a strong background in: MATH, COMPUTER SKILLS & BASIC SCIENCES!!