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Clickers! Select the major monosubstitution product:

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Presentation on theme: "Clickers! Select the major monosubstitution product:"— Presentation transcript:

1 Clickers! Select the major monosubstitution product:

2 Either ortho or para to the stronger activating group! Clickers! Select the major monosubstitution product:

3 Select correct reagents REACTION 1REACTION 2 A:KCN, EtOHHNO 3 B:NaNO 2, HClCuCN C:NaNO 3, HClCuCN D:NaCNNaNO 2, HCl E:NaNO 2 NaCN, HCl

4 Select correct reagents REACTION 1REACTION 2 A:KCN, EtOHHNO 3 B:NaNO 2, HClCuCN C:NaNO 3, HClCuCN D:NaCNNaNO 2, HCl E:NaNO 2 NaCN, HCl

5 Consider this reaction: The first step in the reaction mechanism is: A:Deprotonation of the alcohol. B:Protonation of the methoxyl oxygen. C:Protonation of the aryl ring. D:Protonation of the hydroxyl oxygen.

6 Consider this reaction: The first step in the reaction mechanism is: D:Protonation of the hydroxyl oxygen.

7 Consider this reaction: The next step in the reaction mechanism is: A:Protonation of the alkene. B:Loss of H 2 O to form a carbocation. C:1,2-Hydride shift. D:Proton transfer to the methoxyl group.

8 Consider this reaction: The next step in the reaction mechanism is: B:Loss of H 2 O to form a carbocation.

9 And finally… But you all knew that anyhow, right?


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