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LIPID METABOLISM. HYDROLYSIS ADIPOSE TISSUE 90% of adipose tissue is tryglycerides It supplies energy. Insulation. Provides minor physical protection.

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Presentation on theme: "LIPID METABOLISM. HYDROLYSIS ADIPOSE TISSUE 90% of adipose tissue is tryglycerides It supplies energy. Insulation. Provides minor physical protection."— Presentation transcript:

1 LIPID METABOLISM

2 HYDROLYSIS

3 ADIPOSE TISSUE 90% of adipose tissue is tryglycerides It supplies energy. Insulation. Provides minor physical protection Cholestrol storage

4 GLYCEROL GLUCOSE PYRUVATE GLYCOLYSIS

5 FATTY ACIDS Activation of Fatty Acid

6  -OXIDATION Blue box =  carbon Red box = acetyl CoA

7  -OXIDATION 1.Activation by addition Coenzyme-A 2.  carbon oxidized from CH 2 to C=O (ketone) 3.Molecule split into acetyl CoA and Fatty acid 2 carbons shorter 4.Another Coenzyme-A added to shortened Fatty acid

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9 Each cycle produces 1 acetyl-CoA –18 carbon fatty acid would give 9 acetyl-CoA Cycles required is # of carbons/2 – 1 –18 carbon fatty acid would require 8 cycles Amount of energy from Fatty Acid depends on length of carbon chain –18 carbon fatty acid would 120 ATP

10 LIPOGENESIS Making triglycerides from glycerol and fatty acids Anabolic process Fatty acids made linking 2 carbon acetyl groups (from acetyl CoA) to growing chain Most Fatty acids have an even number of carbons

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12 ESSENTAIL FATTY ACIDS Those needed by the body, but not synthesized within the body in adequate amounts. Found in fish and some plants

13 GLUCOSE TRIGLYCERIDES PYRUVATE GLYCEROL ACETYL-CoA glycolysis gluconeogenesis  -oxidation lipogensis

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