1. Canadian Network For Environmental Scanning in Health Cédric Jehanno Project manager – optimal use of drugs and horizon scanning at INESSS Vice-Chair of CNESH CADTH symposium, April 13, 2015

2. Top 10 New and Emerging Health Technologies Watch List 2015

3. Andexanet Alfa represents a major breakthrough as an antidote to new direct oral anticoagulants in the case of major bleeding emergency surgery Andexanet Alfa for Bleeding Episodes

4. Electrically stimulated underwear is a novel way to prevent bedsores Electrically Stimulated Underwear for Pressure Ulcers

5. Eravacyclin is a new broad- spectrum antibiotic for the treatment of multidrug- resistant organism infections Eravacyclin Antibiotic for Multidrug- Resistance Infections

6. New medication for heart failure may reduce the risk of dying, and improve quality of life Medication LCZ696 for Heart Failure

7. A new type of imaging system may provide additional, useful information for breast cancer detection in woman with dense breasts Molecular Breast Imaging

8. Nivolumab is an immunotherapy agent with promising results for advanced melanoma Nivolumab for Melanoma

9. A portable, hand-held vision scanner that quickly and accurately detects two common vision disorders in children: strabismus and amblyopia Pediatric Vision Scanner

10. Remote monitoring of heart devices may lead to better health and fewer doctor’s visits Remote Monitoring of Cardiac Devices

11. An injectable drug called secukinumab is a new option for the treatment of moderate to severe psoriasis Secukinumab for Psoriasis

12. Toraymyxin improves blood flow and reduce mortality in patients with sepsis Toraymyxin for Sepsis

13. Type of Technology5 devices; 5 pharmaceuticals Care Setting 6 in-hospital; 2 outpatient; 2 GP’s office Potential Treatment Population More than 500 000 per year in 4 out of the Top 10 Key Characteristic Potential patient health benefit as the dominant criteria Characteristics of the 2015 Top 10

14. Come and visit our booth for more information http://www.cadth.ca/en/products/envir onmental-scanning/overview/cnesh