1. Neutralizing Power of Antacids
Due Today:
1. Neutralizing Power of Antacids Pre-Lab
2. Acid-Base Short Lab Report
Homework:
1. Neutralizing Power of Antacids Formal Lab Report
2. Iron Content Analysis Pre-Lab
Neutralizing Power of Antacids

2. Objective Measure neutralizing capacity of a commercial antacid
Determine which brand is most cost effective

3. Procedure Notes Part I: Standardizing NaOH
Completed in Acid-Base Titration Lab

4. Procedure Notes Part II: Titration with simulated Stomach Acid
Use graduated pipettes
Add bromophenol blue indicator
Yellow → Blue
Make sure there is no green tint!

5. Procedure Notes Part III: Stomach acid/Antacid Reaction
Record all pertinent information from packaging
Use graduated pipets
GENTLY heat
Heat no higher than 3
Some solids may remain
Keep track of the # of pipets added

6. Procedure Notes Part IV: Neutralizing excess Stomach Acid
Use GRADUATED pipets
Add bromophenol blue indicator
Yellow → Blue
Make sure there is no green tint!

7. Waste Titrated solutions → dispose in the sink
Excess NaOH → place in large carboy

8. Risk assessment Hydrochloric Acid Sodium Hydroxide Danger
Inhalation Hazard
Corrosive
Sodium Hydroxide

9. moles=M x V calculations Total Moles of HCl added to antacid:
V= (total number of pipets used)
1 Pipet = mL

10. m𝑜𝑙𝑒𝑠 𝑛𝑒𝑢𝑡𝑟𝑎𝑙𝑖𝑧𝑒𝑑 1 𝑡𝑒𝑎𝑠𝑝𝑜𝑜𝑛 𝑥 # 𝑜𝑓 𝑡𝑒𝑎𝑠𝑝𝑜𝑜𝑛𝑠 𝑑𝑜𝑠𝑒
calculations
Moles neutralized per dose
m𝑜𝑙𝑒𝑠 𝑛𝑒𝑢𝑡𝑟𝑎𝑙𝑖𝑧𝑒𝑑 1 𝑡𝑒𝑎𝑠𝑝𝑜𝑜𝑛 𝑥 # 𝑜𝑓 𝑡𝑒𝑎𝑠𝑝𝑜𝑜𝑛𝑠 𝑑𝑜𝑠𝑒
Dose of antacid per dollar
𝑑𝑜𝑠𝑒 𝑐𝑜𝑠𝑡 =𝑑𝑜𝑠𝑒/$

11. 𝑚𝑜𝑙𝑒𝑠 𝑑𝑜𝑠𝑒 𝑥 𝑑𝑜𝑠𝑒 $ =𝑚𝑜𝑙𝑒𝑠/$
Calculations
Moles HCl neutralized per dollar
𝑚𝑜𝑙𝑒𝑠 𝑑𝑜𝑠𝑒 𝑥 𝑑𝑜𝑠𝑒 $ =𝑚𝑜𝑙𝑒𝑠/$
You must collect ALL groups moles/$ values

12. Antacid information Antacid Active Ingredients Price Quantity Dose
Rolaids
$4.99
150 tablets
3 tablets
Tums
$5.79
Mylanta
$6.29
12 fluid ounces
3 teaspoons
Maalox
$5.89
Milk of Magnesia
$6.49
2 teaspoons

13. Cost effectiveness comparison
Antacid
average experimental neutralizing capacity per dollar
theoretical moles HCl neutralized per dose
theoretical neutralizing Capacity per Dollar
percent difference
Rolaids
Tums
Mylanta
Maalox
Milk of Magnesia