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 Preparing undergraduates to succeed in college and beyond in a bioinformatics-rich curriculum  Discussion of existing resources, opportunities, and.

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Presentation on theme: " Preparing undergraduates to succeed in college and beyond in a bioinformatics-rich curriculum  Discussion of existing resources, opportunities, and."— Presentation transcript:

1  Preparing undergraduates to succeed in college and beyond in a bioinformatics-rich curriculum  Discussion of existing resources, opportunities, and challenges  Relevant issues identified in the pre-conference survey include:  How do we encourage math-averse students to embrace quantitative and computational analysis?  How much knowledge and expertise in computer science and mathematics do life science majors need?

2 William Morgan, Sofia Visa The College of Wooster

3 Provide undergraduates in computer science OR biology with an interdisciplinary experience to:  Develop a bioinformatics conceptual framework  Learn to use essential bioinformatics tools  Develop programming skills  Explore questions in bioinformatics  Acquire skills and confidence to work on an interdisciplinary team

4 Segment 1: Develop a shared knowledge base  “Essentials” mini-courses Segment 2: Explore & apply bioinformatics tools, working collaboratively  Topics in computational genomics  Genome Annotation; Genome Evolution; Gene Expression  Weekly structure  Genomics / Programming / Case Study

5 Goal: Predict host-targeted proteins encoded in a pathogen genome 1. Translate ORFs of a Phytophthora genome into protein sequences 2. Based on N-terminal signal peptide, identify putative secreted proteins 3. Based on RXLR domain, identify putative host cell-targeted proteins

6  Textbooks  The Cartoon Guide to Genetics (Updated ed.)  Python for Bioinformatics  Introduction to Computational Genomics: A Case Studies Approach

7  Department & institutional buy-in  Coordinating instructor activities  Weekly course structure  Balancing course content  Student enrollment levels  Fostering student collaboration


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