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Rational, Trial Design, and Results of the ADAGIO Delayed Start Trial C. Warren Olanow, MD, FRCPC Henry P. and Georgette Goldschmidt Professor Chairman Emeritus, Department of Neurology Professor, Department of Neuroscience Director, Robert and John M. Bendheim Parkinson's Disease Center Mount Sinai School of Medicine New York, New York Mechanisms ● Mortality ● Therapeutics
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Schematic Illustration of the Three Primary End Points of the Study Olanow CW, et al. N Engl J Med 2009;361:1268-78.
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Randomization and Treatment of the Study Subjects Olanow CW, et al. N Engl J Med 2009;361:1268-78.
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Baseline Characteristics Olanow CW, et al. N Engl J Med 2009;361:1268-78.
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Results for Primary and Secondary Characteristics Olanow CW, et al. N Engl J Med 2009;361:1268-78.
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Changes in Scores on the Unified Parkinson’s Disease Rating Scale Olanow CW, et al. N Engl J Med 2009;361:1268-78.
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Adverse Events According to Treatment Group Olanow CW, et al. N Engl J Med 2009;361:1268-78.
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Adverse Events According to Treatment Group (cont) Olanow CW, et al. N Engl J Med 2009;361:1268-78.
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Adverse Events According to Treatment Group (cont) Olanow CW, et al. N Engl J Med 2009;361:1268-78.
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