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Finding High Level Evidence in PubMed Presented by Erin O’Toole

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Presentation on theme: "Finding High Level Evidence in PubMed Presented by Erin O’Toole"— Presentation transcript:

1 Finding High Level Evidence in PubMed Presented by Erin O’Toole

2 Objectives Become familiar with: The types of higher level evidence publications Why you would want to use PubMed The content of PubMed MeSH = Medical Subject Headings Two ways to search for higher level evidence

3 Levels of Evidence Systematic Reviews/ Meta-analyses of RCTs Randomized Controlled Trials = RCTs Individual RCTs Mechanism- based Reasoning LEVEL 1 LEVEL 2 Adapted from "The Oxford Levels of Evidence 2". Oxford Centre for Evidence-Based Medicine. LEVEL 5

4 Why Use PubMed?  Not all systematic reviews are published in EBM resources.  It’s FREE! You won’t be at UT Southwestern forever. Loansome Doc service  Produced by National Library of Medicine

5 What’s in PubMed?  MEDLINE – index and abstract of 5600 biomedical journals index = citation and MeSH for article abstract = summary of article  Books and book chapters from NCBI Books  Articles from PubMed Central Over 22 MILLION article records in PubMed!

6 Beware the Basic Search Ratio of systematic reviews to case reports?

7 PubMed Tool: Clinical Queries  Includes search limited to systematic reviews, meta-analyses, and other high-level evidence But wait...  Limited to specific clinical research areas Not all topics covered No economic analyses Comprehensive search has to be done directly in PubMed

8 Search with MeSH Medical Subject Headings “Tags” assigned to articles to describe their content 16 categories of terms, general to specific Automatically EXPLODES your search

9 A live demonstration of searching for high level evidence in PubMed occurred at this point in the presentation.

10 References Heneghan, Carl, and Douglas Badenoch. Evidenced-Based Medicine Toolkit, 2 nd ed., Maiden, Mass.: BMJ Books/Blackwell Pub., OCEBM Levels of Evidence Working Group. "The Oxford Levels of Evidence 2". Oxford Centre for Evidence-Based Medicine. QUESTIONS? Erin O’Toole


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