1. UNC Office of Technology Development Seminar February 2, 2012

2. About ibiliti

3. 3 ibiliti Builds Momentum We accelerate the growth and commercialization of emerging medical technologies by uniting human, intellectual and financial assets toward significant discoveries that improve lives.

4. 4 History of ibiliti  Non profit, 501(c)(3) state-wide organization  Focused exclusively on devices, diagnostics, imaging, healthcare IT  Received $2.5 million state grant administered by NC Biotechnology Center  Founded 2009

5. 5 ibiliti Board Members Board MemberExperience Greg Davis, ChairmanFmr CEO Tryton Medical, Guidant Sam Taylor, Vice ChairmanPresident, NCBIO Ken LeeGeneral Partner, Hatteras Venture Partners Ken AtkinsExec. Dir., Wake County Economic Development Charles GoldsteinVP Research, BD Technologies Tim GuptonPartner, HPG Matt JenningsCEO Phillips Plastics, fmr Teleflex, BioEnterprises Fred McCoyVice Chairman, Synecor Barry MyersProf. Duke, EIR Pappas Troy NagleProf. UNC/NCSU Bob WilhelmProf. UNCC Mary Beth Thomas (observer)NC Biotechnology Center

6. 6 Cindy Clark, President 20 years of life science experience CEO, Sirga Advanced Biopharma, a NCBC TEAM company President, Phase Bioscience President, Bell Atlantic Internet Solutions, North Univax Biologics, CV Therapeutics JD Washington College of Law BA Wesleyan University

7. About North Carolina’s Medtech Industry

8. 8 400+ Companies Call North Carolina Home 9,000+ people employed directly; 21,000+ indirectly

9. 9 North Carolina Medtech Industry Statistics Experienced Talent Pool – 9,000+ people employed directly; 21,000+ indirectly Significant Investor Support – 100+ VCs with medtech portfolios invested in NC cos. Strong Community Anchors – Becton Dickenson, BioMerieux, BSN Medical, Cook Medical, Covidien, Dupont, Ethicon, LabCorp, NovoNordisk Engineering, Sandoz (Novartis), Siemans Medical, Sirona Dental, Smith & Nephew Spine and Biologics, Suntech Medical, Teleflex Medical

10. 10 North Carolina and Medtech—a perfect match Technology is in our DNA Manufacturing is our strong Suit Southern hospitality Outstanding University with world-class BME schools Convergence of Technologies Foundation of diverse medtech companies

11. 11 North Carolina Ranks 17 in Employment, Payroll and Sales StateEmploymentPayroll ($1,000s) Sales ($1,000s) United States422,77824,600,669135,921,967 California83,9995,253,89126,341,566 Minnesota26,8621,707, 5086,775,042 Massachusetts23,9071,596,6688,288,236 Florida21,6681,154,6206,476,288 Ohio12,383528,6142,819,114 Tennessee8,349428,0352,455,967 North Carolina8,407425,6852,208,625 2007 LewinGroup data for AdvaMed

12. 12 Recent High-Profile Companies TransEnterix – Spider minimally invasive surgery device Tryton Medical – bifurcated bare metal stent Tear Science – device for diagnosis/treatment of dry eye Pioneer Surgical – orthopedic devices nContact – minimally invasive cardiac surgical devices Oncoscope – imaging system epithelial cell cancer Bioptigen – ophthalmic imaging

13. 13 Major Industry Suppliers Nypro Flextronics Patheon Sanmina SCI Plexus Insight Product Development Catalent

14. ibiliti Programs

15. 15 ibiliti Programs Job board and job connections Investor connections (VCs, angels, other) Service provider network Expert-on-Call program Grant writing services Tech scouting Quarterly networking meetings Facilitation of NC’s dialogue on change with FDA’s CDHR

16. Annual medtech conference

17. Medical Innovation and Commercialization Alliance (MICA) Powered by launchibiliti

18. 18 MICA : Medical Innovation and Commercialization Alliance Accelerate the commercialization of medical technology ideas from doctors, allied health professionals, entrepreneurs & inventors in Western North Carolina that will improve patient care Unique collaboration with Mission Health – One of largest healthcare systems in NC – Named top 15 hospitals in US by Thompson Reuters Pilot program began 2011

19. 19 MICA Overview Regional Advisory Board National Advisory Board Hospital Investment Board Physicians Staff Community Other No Current Interest - Open Pool Eligible for In-Kind Development No Current Interest - Open Pool Eligible for In-Kind Development Funded Development Program Grants In-kind services Low interest loans Equity Funded Development Program Grants In-kind services Low interest loans Equity License License Fee Warrants Equity Royalties Champion Patent Prototype Business Plan Other Champion Patent Prototype Business Plan Other Large MedTech Small MedTech Entrepreneur Hospital Innovation Forums 1-1 Interviews w/ Staff On-line Portal Hospital Innovation Forums 1-1 Interviews w/ Staff On-line Portal 2-3 technologies/ yr/region

20. 20 MICA Partners BD Technologies - $10K prize, prototype work Phillips Plastics – Prototype work J&J COSAT - $250K-$1M grants & matching $ Western Carolina University – Prototype & Business Plan Buncombe County Economic Development UNC/NCSU BME – Prototype work UNC MBA – Business plan development Gilero – Prototype work Synecor – Animal studies

21. 21 MICA Regional Advisory Board Board MemberExperience Roy CrowninshieldZimmer, Tutogen, Entreprenuer Richard Bock Vascular Surgeon, Entrepreneur, Asheville Radiology Brian Nass Mission Health Quality, Mayo Clinic Commercialization, Entrepreneur Ed Wright Welch Allen, Suntech Medical, Entrepreneur, WCU Carlton MurrayCarolina Financial Steve WoodyG3 Medical, Medtech Entrepreneur John LockeMission Healthcare Foundation Pam LewisAdvantage West, Asheville EDC

22. 22 National Advisory Board Board MemberExperience Charles GoldsteinBD Technologies Scott SewellCook Medical John UhrinCredit Suisse Tony VoiersEthicon Brian CarneyHarbert Ventures Bob MorffHatteras Ventures Bibhash MukhopadhyayJ&J COSAT Bryant MooreMedtronic Ali BehbehaniNEA Matt JenningsPhillips Plastics Matt ReikeQuaker Bioventures Jim O’ConnellSafeguard Scientific Henry TungSmith & Nephew Garheng KongSoffinova Ventures Kenny AndersonSunTech Medical

23. 23 Diabetes Point of Care Network : DNET 3 Unique public/private partnership : UNC, BD Technologies, ibiliti Purpose: identify and commercialize point of care diabetes technologies to serve needs of underserved diabetes patients & their care-givers Includes undergraduate & graduate training Drs. John Buse & Michael Ramsey, PIs NIH grant application pending, other funding sources being sought First project: Simple, inexpensive Point-Of-Care Blood Glucose Test to enhance & expand patient self- management of diabetes

24. For More Information: Cindy Clark President ibiliti 919.508.6214 cclark@ibiliti-nc.com