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Published byNathaniel Knipe Modified about 1 year ago

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Mitochondria

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Mitochondrial Structure (cont.)

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Mitochondrial Structure

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Mitochondrial Structure (cont.) MITOCHONDRIA MODELED INTERFIBRILLAR MITOCHONDRIA SUBSARCOLEMMAL MITOCHONDRIA CAPILLARY

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4 444

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The Respiratory Chain I = NADH - CoQ Reductase Complex II = Succinate - CoQ Reductase Complex III = CoQ - Cytochrome C Reductase Complex IV = Cytochrome Oxidase ETS = 12 or more different electron carriers. Grouped into 4 complexes

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Proton - Motive Force

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Biochemical Energetics

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Cytosolic NADH + H + Inner mitochondrial membrane 71% protein Shuttle Systems 1. Glycerol Phosphate - Fast Twitch - (Type II) Results in FADH 2 in matrix 2. Malate - Heart, liver, slow twitch Results in NADH + H + in matrix

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Translocation of ATP, ADP, and inorganic phosphate (Pi) Cytosolic side Inner membrane Matrix side ADP 3 - ATP 4 - H 2 PO 4 - H + ADP - ATP antiport Pi - H + symport

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