1. NTP Radioisotopes SOC Ltd
A subsidiary of Necsa Ltd
Pelindaba, South Africa
NTP’S ROLE IN NUCLEAR MEDICINE GLOBALLY AND COOPERATION WITH BELGIUM
Mapula Letsoalo
2013 October 23

2. Depleted Uranium Fabrication Facility (Pelindaba)
NTP Radioisotopes (Pty) Ltd
Contents
Role in global Mo-99 supply
Role in SA nuclear medicine
Continued relations with IRE

3. NTP located at the Necsa Pelindaba Site
Geographical Location of NTP Radioisotopes
Geographical Location of NTP Radioisotopes
Pretoria
Johannesburg
Soweto
OR Tambo
NTP located at the Necsa Pelindaba Site

4. The Real And Lasting Victories Are Those Of Peace
In 1991, the South African
government signed the
Non-Proliferation Treaty (NPT)
and became the first and only
nation to voluntarily declare and
dismantle its nuclear weapons
And they shall beat their swords
into ploughshares ... – Isaiah 2:4

5. Mo-99 Production & Related Facilities5 3 1 4 2
- Radiochemical Production Plant
- Commercial Office
- Radiopharmaceutical Production Plant
- Radioanalytical Labs
- SAFARI-1

6. SAFARI-1 Reactor
SAFARI-1 Nuclear Reactor

7. Mo-99 Production at NTP Mo-99 Production at NTP SAFARI-1 Reactor
Target Plate Irradiation
Nuclear Fuel Assemblies
Enriched Uranium Inventory
Fuel Production Plant
Target Plates
Irradiated plates
Depleted Uranium Inventory
Waste
Nuclear Waste Management
Radiochemical Production Plant
Chemical Extraction and purification of Mo-99
Waste Disposal & Storage Facilities
Transport Container Design Manufacture, License
NTP Generator Manufacture
International Market
Local & International Users

8. NTP Product Portfolio NTP - IRE Cooperation
Collaborative partnership since 1997
Mo-99 Supply crisis
Increased production output
Total: Ci/week

9. Radioisotope Source Containers Radioisotope Source Containers
Depleted uranium fabrication facility
Radiochemical Transport Containers (1 500 Ci Mo-99, 125kg)

10. Subsidiary Companies Subsidiary Company
NTP Logistics is a joint venture company between NTP Radioisotopes (51 %) and a BEE partner
Specialize in managing the logistics of dangerous goods including radioactive materials.

11. Conversion of Mo-99 Production to LEU
NTP Product Portfolio
Conversion of Mo-99 Production to LEU
2007
Theoretical feasibility studies
2008
Cold and depleted uranium experiments
2009
NNR approval received for test stage
Hot runs commence
2010
Submission to Regulators (June)
Validation runs (July)
NNR approval routiine ops (Sept)
FDA approval for use in US (Nov)
2011
Routine supply of LEU Mo-99 (June)

12. Medicals Facilities Medical Facility 3 3 2 2 1 1
- Medicals & Industrials
- SAFARI-1
- Cyclotron facility 1 1

13. Nuclear Medical Isotopes & Related Products Radiopharmaceuticals
NovaTec-P Tc-99m Generator, Cold kits
F-18 FDG
I-131 Capsules, Solution and MIBG
New
Lu-177 dotatate
F-Choline
PET-CT Image

14. Subsidiary Companies Subsidiary Company
NTP has a 100% shareholding in AEC-Amersham SOC Ltd
Exclusive distributor in Africa of NTP's radiopharmaceutical products as well as a range of life science research and other products.

15. Corporate Social Investment
PET/CT Scanner donated to people of Western Cape
Located at Tygerberg PET/CT Centre
Official opening - April 2012

16. Subsidiary Companies Subsidiary Company
Fully-owned subsidiary company NTP Radioisotopes (Europe) S.A.
Established on 1 February 2013
Located in Belgium – IRE site
Manufacturer and distributor of gamma-radiography equipment used in the non-destructive testing (NDT) industry, including sealed radioactive sources containing Ir-192, Se-75 and Co-60, as well as the GammaMat range of NDT projectors and accessories
Also manufactures a range of Ir-192 brachytherapy products

17. and to our country’s global standing.
Subsidiary Companies
Conclusion
Necsa/ NTP’s nuclear technology is making a major contribution to the economy
and to our country’s global standing.

18. Subsidiary Companies
Thank you very much!