1. A Unique Summer Experience Without Traditional Course Work: Balancing an Internship and Additional Research Janelle Noel, M.S. KUMC Biostatistics Ph.D. Graduate Student

2. Outline Process of Obtaining an Internship The Internship –Life as an Intern Daily Schedule Expectations –Projects GRA Project Work-School-Life Balance Most Valuable Lessons Learned

3. Process of Obtaining an Internship

4. Process of Obtaining an Internship: Where should you look for an internship? Watch for emails that go out from the department American Statistical Association’s webpage –www.amstat.orgwww.amstat.org

5. Process of Obtaining an Internship: Where should you look for an internship?

6. Watch for emails that go out from the department American Statistical Association’s webpage –www.amstat.orgwww.amstat.org Indeed, LinkedIn, and/or Career Builder

7. Process of Obtaining an Internship: Where should you look for an internship?

8. Watch for emails that go out from the department American Statistical Association’s webpage –www.amstat.orgwww.amstat.org Indeed, LinkedIn, and/or Career Builder Look at websites from specific company –Research Triangle companies –Pharmaceutical companies: Novartis, Eli Lilly, Bayer, etc. –Hospital networks and other medical associations

9. Process of Obtaining an Internship: When should you look for an internship? Don’t wait! Announcements for summer internships come out as soon as November –Application deadlines are usually in late December or early January

10. Process of Obtaining an Internship: What should you have prepared? Cover letter –General –Specific for each company Résumé/ Curriculum vitae (C.V.) Personal statement Questions for future employer/company Answers to common interview questions

11. Process of Obtaining an Internship: Once accepted, what steps do you need to take to make it a reality? Step 1: Tell the necessary people Step 2: Get a game plan! –Where will you live? –How will you get there? –Determine finances/budget –Create a timeline Step 3: Organize your materials Step 4: Continue to have open communication with your future boss/company until your start date

12. PRIMARY RESEARCH TEAM

13. The Internship

14. The Children’s Hospital Association (CHA) –Legacy companies 1.Children Health Corporation of America (CHCA) 2.National Association of Children’s Hospitals and Related Institutions (NACHRI) Two Campuses: 1.Overland Park, KS 2.Washington, D.C. CEO: Mark Wietecha, M.S., M.B.A Mission Statements: “We are committed to improving access to quality care, reducing costs and keeping the unique needs of children at the forefront of health care reform implementation.”

15. The Internship Title: Analyst Intern Company Branch: Statistical Solutions Research Team: Matt Hall, Ph. D. (Principal Biostatistician) Troy Richardson, Ph. D. (Biostatistician) Jay Berry, M.D., M.P.H. (Research Clinician/ Assistant Professor)

16. The Internship: Overview Duration: 12 weeks Day 1: Orientation Week 1: Compliance, IT, Exploring datasets, and learning the ICD-9 coding system Week 2: PI in-person visit Week 3 : … Week 10: Weeks 11/12: Documenting/Summarizing progress and verifying codes programming, literature reviews, conference calls, weekly meetings, projects, learning their corporate culture, making caffeinated coffee, eating fruit & nuts, and introducing myself to 100+ people

17. Life as an Intern: Daily Schedule TimeActivity 7:00 a.m. – 8:00a.m.Arrive, make coffee, read emails, read The CHAT, and the occasional conference call 8:00 a.m. – 10:00 a.m.Working on task for the day 10:00 a.m. – 10:30 a.m.Weekly meetings, company meetings, grab a snack from the bistro 10:30 a.m. - 11:30 a.m.Working on task for the day 11:30 a.m. - 12:30 p.m.Lunch ( Lunch was provided on Wednesdays ) 12:30 p.m. – 2:00p.m.Working on task for the day 2:00 p.m. – 3:00 p.m.Popular conference call hour on any given day 3:00 p.m. – 4:00 p.m.Working on task for the day and summarizing the day 4:00 p.m. – 5:00 p.m.Leave for the day

18. Life as an Intern Expectation Prior to Internship Reality Complete a projectComplete an aim of a project and work on multiple side projects Structured daysFlexible schedule Work at a cubicleWork in an office Conference calls are not awkwardConference calls can actually be fairly awkward

19. Project I: AHRQ R21 Grant Background: Individuals living with multiple chronic conditions (MCC) –receive inadequate quality of health care –experience suboptimal health outcomes Health care systems are poorly designed to provide high quality of care for children with multiple chronic conditions (CMCC) and their families. Relevant to public health –rapidly advance our understanding of the U.S. population of CMCC

20. Project I: AHRQ R21 Grant Primary Aim: Adapt a publicly available, comprehensive diagnosis classification scheme developed by AHRQ to count the number of chronic conditions, name each chronic condition, and describe the combinations of chronic conditions endured for each CMCC. Data: Healthcare Costs and Utilization Kid’s Inpatient Database 2009 (HCUP KID) and Medicaid data from Truven Health Analytics (2009-2012) HCUP KID: 3.4 million individual records Medicaid data: 8.6 billion records Exclusion Criteria: Normal newborns and only one chronic condition

21. Project I: AHRQ R21 Grant

22. My role : Cleaning data Sub-setting data Presenting data findings and problems to research team Conducting sub-analyses on healthcare cost and utilization Building laying out framework for Classification and Regression Tree (CART) model

23. Project II: Side Project Preliminary analysis Objective: Determine if a trend exists year to year regarding the percentage of discharges and length of stays in children’s hospitals (CH) using two different definitions Data: HCUP KID years 2000-2012 Method: Cochran—Armitage Trend Test Definition #1Definition #2 1 = Freestanding CH1 = Freestanding and Non-Freestanding 2 = Non-Freestanding CH2 = Other hospitals 3 = Other hospitals

24. Project III: New Proposed Projects

25. GRA Project

26. Two part genomics project Part I: Determine differentially expressed (DE) genes found among the different DE analysis methods -pre and post treatment Part II: Assess 1)control of the type I error rate under the null hypothesis assuming unpaired or paired measurements through a simulation study 2) impact of ignoring the paired design among samples (Summer ‘14)

27. GRA Project: Part I Paired Methods *Excludes EBseq from Venn Diagram Unpaired Methods Figure 1: Number of Differentially Expressed Genes (Statistical Framework) Frequentist Methods N=4543 Bayesian Methods N=2609 Figure 2: Number of Differentially Expressed Genes (Method’s Statistical Theory)Table 1: Number of Common Differentially Expressed When Methods Overlap

28. GRA Project: Part II

29. Null Scenarios Fold change (FC)/ Power scenarios

30. GRA Project: Part II

31. Work-School-Life Balance

32. Work-School-Life Balance….Ha! Work School Life

33. Most Valuable Lessons Learned

34. Importance of programing skills Government data is messy Document, document, document Don’t be afraid to ask Importance of productive conference calls Communication skills can always be improved Awareness of professionalism

35. Bloopers What happens when you let two grown men decorate your office? Every office needs at least one running joke…

36. Drs. Brooke Fridley, Jo Wick, and Matt Mayo Jackie Jorland Drs. Matt Hall, Troy Richardson, Jay Berry Acknowledgements

37. Questions