1. Jake Gelsinger David Hills Derick Jensen Ben Placzek

2.  Brief Procedure Introduction  Vein Analysis  Syndaver Labs Synthetic Vein Tissue Testing  FEA Synthetic Vein Tissue Analysis  FEA Vein Environment Modeling Analysis  Prototype  Assembly/Construction Progress  Proof of Concept Overview

3. 1)Prepare the Pacemaker Pocket 1)Detach Pacemaker Leads 2)Prepare Leads 3)Insert LLD (Lead Locking Device) 1)Expand LLD to lock in place 4)Deploy Laser Over Lead and LLD 5)Lase through all Fibrous Tissue Problem Lies in Fibrous Occlusions Vein Extraction Procedure

4.  Testing Procedure  Lowering tissue onto laser tip (12 french)  Reading force tissue exerts on laser on a scale  Increase force by lowering tissue until rupture  18 Tests were conducted  6 tests at three different angles were tested  Tried to model the angles that may occur during surgery  Each test lasted an average of 1 minute and 53 seconds Syndaver Labs Tissue Testing

5.  COMSOL was the software used  Limits of Software  Do not know true material properties of Syndaver tissue  Cannot model tearing  Cannot model soft tissue  Non-linear  Non-homogeneous  Transient response Sythetic Vein FEA

6.  Software Used was SolidWorks  Limits of Software  Cannot model tearing  Unknown material properties (Poisson’s Ratio)  Cannot accurately model vein constraints  Cannot model soft tissue  Non-linear  Non-homogeneous  Transient response Vein Environment FEA

7.  Design made to minimize cost while preserving durability and usability  Construction was difficult to get coordinated  Mind Studios vs. Machine Shop  End Result  Proof of Concept Design  Recommendations Prototype