1. Prof. Dr. Willem Kollf (1911 Leyden Netherland) -Emeritus Prof. Dr. Internal Diseases,Surgery, Bioenergy, Specialist.UTAH 39 th EDTA Congress- 2002-Copenhag

2. Kollf used firt hemodialysis device in 1940. Dr Scribner used first shunt in 1960 The First Renal Diseases Union was established in United Kingdom in 1956. The second one was established in France in 1960. Nephrology Sections have been establishing since 1960. The first hemodialysis center of the world was established in New York in 1956. 1450 patients treated by Hemodialysis in 1970 by USA Gootschalk Committee. But this number was not enough, because approximately 4100 or 6300 patients had to wait their death. World’s first ever kidney transplant was successfully performed on monozygote twins in 1954. (Joseph Murray, Boston). The first cadaveric transplantation was successfully performed in 1963. First Practices in the World

3. The first seeds of Turkish Nephrology were firstly sown in our country in 1950s.. Science of Nephrology rapidly started to develop in 2000s. Developments increased in 1960s. The practices accelerated rather fastly in 1970s. Having displayed in advance a rather slow development as a result of individual endeavor and acts of self-giving. Nephrology, thanks to the establishment of hemodialysis centers in the 80s made progress. And managed in the 90s to keep up with world standards. Turkish History of Nephrology, A Summary

4. When We Assess Dialysis in a Historical Concept;  The Dialysis performances have been developing parallely with worldwide development.  But the necessity of obtaining tools and devices from abroad.  The difficulties of wasting time for public acceptance in dialysis, insufficiencies of educated staffs, wantonly arguements cause to delay in processes during treatment. Turkish History of Nephrology, A Summary

5. Dialysis and transplantation maintained as monotonous practices until 1980s. And then they became to make progress with new establishing centers. Real acceleration was viewed in 1990s. Recently the numbers of dialysis centers have been raising strikingly. Only 234 dialysis centers existed in 1998 and their quantities reached 391 by the end of 2001. According to the datas of the Ministry of Health the dialysis centers’ quantities reached 472 in 2003. There were 518 dialysis centers in 2004 and 554 in 2005.

6. 19 centers in 1980. (E.Ertuğ-Bülent Erbay ) 19 centers, 600-700 patients in 1985 (K.Önen) 28 centers in 1988 (S. Yeğinboy.) 256 centers in 1998 (Ministry of Health ) 472 centers, 25577 patients in 2003 (Ministry of Health ) 518 centers, 29775 patients in 2004 (Ministry of Health) 579 centers, 33487 patients in 2005 (Ministry of Health) Ülkemizde Tarihsel Gelişim İçinde Yıllara göre Hemodiyaliz Merkez Sayısı

7. The History of Turkish Registration Systems of Nephrology – Dialysis and Transplantation Turkish Society of Nephrology’s (TSN) Registration Systems - Turkish Society of Nephrology started with İstanbul Registration Systems in 1989. - Afterwards, TSN has started to became to its current situation since 1990. National Dialysis and Transplantation Datas of Ministry of Health Ministry of Health has started to prepare extensive registration system since 1996. Renaliz: Issue:13, Year 5, Page :1, 2003,

8. Existing Public and Private Dialysis Centers in Turkey-2005 Name of Institution CenterDeviceNo. of Patients Number% % % Ministry of Health29050299934,7958728,6 University498.5103111,93209 9,6 Private24041.5461653,42069161,8 TOTAL579100864610033487100 Ministry of Health- 2006

9. Ministry of Health 2005 Number of Total Kidney Transplantations by the End of 2005 (1975-2005) Total: 8321 Alive: 6120 73.55 % Cadaver: 2201 26.45 % Total: 8321 Alive: 6120 73.55 % Cadaver: 2201 26.45 %

10. ESRD Patients1.681.000 HD1.158.000 PD 141.000 RTx 382.000 World Population 6,3 billion World Population and Number of ESRD, HD, PD and RTx Patients TSN, 2004 Registry, Year: 2005.

11. Approximate annual growth rates  World Population1.2 %  ESRD6 %  HD6 %  PD6 %  RTx5 % Annual Growth Rate of World Population and Number of ESRD, HD, PD and RTx TSN, 2004 Registry, Year: 2005.

12. Gross Mortality Rate in Turkey and World (Nephrol.Dial. Transplant 2002; 17: 2092). Expansion Rate of RRT Stock (%) Gross Mortality Rate of RRT Patients (%) USA (1999)919,7 JAPAN (1997)7,89,3 EU (15 Countries) 8,2 (2,3-13)10,4 a TURKEY17 b 9,4 a Death range on RRT in Europe (pmp) is 35-89 b HD 18,5 %, CAPD 6, R %, Tx 1,7 %. a Death range on RRT in Europe (pmp) is 35-89 b HD 18,5 %, CAPD 6, R %, Tx 1,7 %. TSN, 2004 Registry, Year: 2005.

13. Total RRT Expenses ($) Treatment Modality TurkeyFranceGermanyJapanUSA HD22.75978.94744.50046.000 CAPD22.35023.68429.000-41.000 APD25.714---35.545 RTx (First Year) 23.39329.60540.00050.00060.000 RTx (Second Year) 10.028--19.00027.000 Total RRT Expenses in Turkey, France, Germany, Japan and USA (Erek et al. Nephrology 2004; 9: 33-38). TSN, 2004 Registry, Year: 2005.

14. Etiology of Incidence End Stage Renal Disease Patients (2000 ) N:5073 0510152025 Etyology Unknown Other Interstial Nephritis Cystic Renal Diseases Urologic Reasons Diabetes Mellitus Hypertension Chr. Glomeruloneph. TSN, 2004 Registry, Year: 2005.

15. Etiology of Incidence End Stage Renal Disease Patients (2004 ) Etiology of incident in ESRD patients (2004) 23,6 6,8 3,9 5,8 13,4 17,2 25,3 4,0 051015202530 Etiyology unknow Miscellaneous Cystic renal diseases Chronic interstitial nephritis Urologic disease Chronic glomerulonephritis Hypertensive renal disease Diabetes mellitus % of patients Etiology of Incidence End Stage Renal Disease Patients (2004 ) 23,6 6,8 3,9 5,8 13,4 17,2 25,3 4,0 051015202530 Etiyology unknow Miscellaneous Cystic renal diseases Chronic interstitial nephritis Urologic disease Chronic glomerulonephritis Hypertensive renal disease Diabetes mellitus % of patients TSN, 2004 Registry, Year: 2005.