PRBC 1 in 5000 Plasma 1 in 2000 Platelets 1 in 2000 IVIG Cryoprecipitate Stem cells
HOST M = F Recent surgery Active infections Recent transfusion Cytokine treatment Thrombocytopenia Increased age Ethanol use Tobacco Severe illness DONOR Multi-parous female donors Prolonged blood storage
What is the #1 cause of #1 transfusion related mortality? What transfusion reaction is very under reported and under-recognized? What can any blood product cause? What should you think about if there is any clinical change within 6 hours of transfusion? Who is the most important person to recognize TRALI?
Supportive Good prognosis Question all transfusions!