4 Pollogen develops & markets advanced solutions for the aesthetics market As technology leaders, we continuously challenge ourselvesto deliver innovation withgenuine added value foraesthetic professionals.
5 We believe that every customer deserves to benefit from the best of all worlds: safe, pleasant and non-invasive treatment, as well as long-lasting results that can be seen and felt immediatelyTo contend with this challenge, we develop innovative technologies, manufacture smart & user-friendly systems and offer a broad variety of treatments with proven results.Above all, we redefine the standards in the world of aesthetics and are committed at all times to give you more…Pollogen - Expect more
6 Over 60 distributors worldwide More Global presenceOver 60 distributors worldwide
7 More ResultsClinically proven Peer reviewed papers in leading medical journals confirming the safety and effectiveness of Pollogen’s technologies.
8 More PartnershipWith Pollogen, you have a true partner Pollogen will accompany you the whole way and provide you with a comprehensive range of services of exceptional standard:Updates on new technological developmentsProduct trainingClinical supportTechnical supportSupply of marketing materialsDirect communication with the sales managerComprehensive marketing consulting and support
9 From small niche to a $4.4B market More OpportunitiesFrom small niche to a $4.4B marketIn the past decade, the global aesthetics market has grown at a double-digit pace, developing from a small niche to a $3.3B market in 2010.Despite the global recession, consumers continue to invest in beauty treatments, & the market is expected to reach $4.4B in 2015.Source: BCC Research
10 More InnovationsPollogen® is a world leader in innovative, clinically proven, aesthetic solutions for facial treatments and body sculpting.
11 More LeadershipDr. Zion Azar, PhD, Founder and Chairman of the Board. Founded Radiancy & PolyOptics. Dr. Azar has a PhD in physics from Tel-Aviv University.Mr. Amichai Bar-Nir, CEO. Mr. Bar-Nir has proven management experience in leading companies through rapid growth and new market penetration. In the past he managed hi-tech companies such as Cognifit and Bi-Plan.Mr. Moshe Shneor, C.P.A., CFO and COO. Mr. Shneor was a senior executive at Ernst & Young where he was responsible for global standardization of Israeli companies on NASDAQ.The management team includes VP’s with over 100 years of cumulative experience in the field, including clinical studies, sales, regulations, R&D and marketing.
13 Introducing… Where superior aesthetic treatments meet RF technology to create a breakthrough skin-care platform
14 Product OverviewDesigned with the aesthetic professional in mind, geneO+ integrates Pollogen’s new patented OxyGeneo technology with renowned TriPollar technology.geneO+ delivers superior skin nourishment and oxygenation together with clinically proven anti-aging results.The combination of TriPollar RF and OxyGeneo improves skin quality both at the epidermis and dermis layers delivering long lasting results
15 Business benefits for clinics New treatment options and increased customer flowPosition your clinic as a leader and gain an advantage over your competitors with cutting-edge technology and designIncreased income & quick ROIAffordable product entry priceCharge premium price for treatmentsIncrease repeat customers and customer loyaltygeneO+ treatments are an ideal opportunity to upsell home use cosmetics/treatmentsJoin the success! Be one of the thousands of clinics worldwide that offer patented TriPollar & OxyGeneo Technologies!
17 Advantages of OxyGeneo & TriPollar OxyGeneo - A 3 in 1 skin care treatment to actively nourish, vitalize and hydrate the skin: Exfoliation of the outer skin layer Infusion of revitalizing nutrients Oxygenation of skin generated from withinTriPollar RF – The 3rd generation RF anti-aging technologyWrinkle reductionSkin tighteningSafe, effective and pleasantImmediate and long term results
18 Protocol according to indication Treatment focused on fine lines and wrinkles -6 weekly sessions, followed by monthly touch up session.First OxyGeneo (NeoRevive or NeoBright ~8 min) and then TriPollar (full face ~30 min)The OxyGeneo treatment exfoliates the stratum corneum and enables better impact of the RFTreatment focused on improving skin texture and nourishment6 weekly sessions, followed by monthly touch up sessionFirst TriPollar (full face ~20 min) and then OxyGeneo (NeoRevive or NeoBright ~8 min)The RF treatment increases blood circulation and improves penetration of the active ingredients of the gel.Note: both protocols can be finalized with NeoMassage session (~5 min)
21 OxyGeneo TechnologyNatural hot springs have been known through the ages for their therapeutic benefits, allowing minerals to be effectively absorbed through the skin to revitalize body cells.Similar to the natural hot springs effect, OxyGeneo™ is the world’s first technology that significantly accelerates the absorption and optimal utilization of nutrients by the skin using our exclusive Capsugen and specialized Gels.
22 OxyGeneo TechnologyHarnesses the body's natural mechanisms to deliver 3 effective treatments simultaneously:Exfoliation of the outer skin layerInfusion of revitalizing nutrients with Pollogen’s unique skin care formulasNatural skin Oxygenation from withinOxyGeneo’s “3 in 1” approach creates an optimal environment for the skin to absorb essential nutrients both during and after treatment.OxyGeneo uses disposable and easy to sterilize components that ensures maximum hygiene during every treatment.Each treatment includes a unique combination of Capsugen™ and gels developed by Pollogen from natural ingredients
23 OxyGeneo - How it worksPollogen’s unique Capsugen™ is composed of sodium bi-carbonate and citric acid. Our exclusive gel contains natural active ingredients.When the effervescent Capsugen™ comes in contact with the exclusive treatment gel on the skin surface an immediate reaction is triggered.This reaction induces the OxyGeneo effect that simultaneously:Exfoliates the skin’s outer layerPrepares it for infusion of active ingredientsInfuses the natural active ingredients deep into the epidermisEnriches the area with O2 rich blood
24 OxyGeneo - How it worksOxyGeneo produces countless minute CO2 bubbles which gently burst on the skin surface.The OxyGeneo applicator is designed to degas the CO2 bubbles from the gel and infuse them into the epidermis.The applicator’s frequency and amplitudes are specifically designed to:Produce a kinetic force that optimizes the chemical reaction generating CO2 bubbles and:Enable optimal penetration of CO2 bubbles into the epidermis.
25 OxyGeneo - How it worksThe outcome is a CO2 rich environment on the skin's surface*.The body responds by:Sending O2 rich blood to the areaIncreasing capillary blood flowIncreasing metabolism of the skin cellsThe desired result: Optimal absorption of the active ingredients by the skin* The chemical reaction between the Capsugen and the gel that generates CO2:
26 OxyGeneo and The Bohr Effect C02 rich environment & infusion ofactive ingredientsOxygenation of skin cells &skin rejuvenationThis C02 rich environment induces a physiological response called the BOHR EFFECT leading to increased tissue oxygen.
28 TriPollar® Technology TriPollar 3rd generation RF technology:TriPollar utilizes RF energy to induce collagen & elastin regeneration in the dermis layer. Leading to:Smoother and tighter skinFine lines and wrinkles reductionImproved skin texture
29 Pollogen’s Breakthrough TriPollar Technology 3rd generation TriPollar RF - applies conductive RF to the skin via 3 or more electrodesEnergy is focused in the target area for optimal effect – not requires coolingVolumetric heating generates clinical effectThe most pleasant RF treatment due to focused energy field allowing low power consumption
30 TriPollar® Preparation Gel The matching fluid for the TriPollar treatment is the TriPollar Preparation Gel.The TriPollar preparation gel should be applied on the treatment area before starting the TriPollar RF treatment.The gel lubricates the area and allows smooth movement of the applicator on the skin.Has a high electrical resistance forcing the electrical current to enter deep into the skin, avoiding the current from flowing on the surface and creating sparks
31 Comparison of TriPollar® to other RF technologies ImageClinical targetPowerPain LevelCoolingVisible Clinical ResultsMono PolarCollagen fibersHigh( W)Might be Very PainfulAlwaysAfter monthsUni Polar(RF radiation)Very hotBi – PolarDermis & hypodermisMedium(10-200W)May be PainfulMay beAfter days / weeksTriPollar®Focused energy on dermis & hypodermisLow(5 – 50W)No Pain PleasantNoneImmediate & long term. supported by clinical and histopathological studies
34 EVALUATION OF SAFETY AND EFFICACY OF THE TRIPOLLAR® TECHNOLOGY FOR TREATMENT OF WRINKLES Steven D. Shapiro MD & Amos Leviav MDStudy Objective:To evaluate the safety of the apollo™ system for treatment of wrinkles and rhytides.To evaluate the efficacy of the apollo™ system for treatment of wrinkles and rhytides.Methods:Subjects: 37 Female subjects were recruited - 37 completed all treatments, 3 lost to follow-up due to travel or change of residence.Visits: 8 Weekly treatments, Follow-Up at 1 month and 3 months after treatment 8.Two sites:Steven Shapiro MD (Dermatologisit) – Gardens Dermatology and Cosmetic Surgery Center, Florida USAmos Leviav MD (Plastic Surgeon) - Kaplan Hospital, IsraelSTUDY # 1
35 ResultsSafety No unexpected adverse side effects were detected or reported.All subjects reported no pain or mild pain during the treatments.EfficacyA downgrade of at least 1 score in Fitzpatrick scale was found in 94% (1st reviewer) and 97% (2nd reviewer) of study subjects.Subjects satisfaction questionnaires revealed high level of satisfaction.PI’s scoring of subjects’ facial skin appearance at baseline and 3 at month FU demonstrated average reduction of 1.55 (Dr. Leviav) and 2.4 (Dr. Shapiro) .ConclusionsThe results of this study clearly indicate that the TriPollar technology offers a non-invasive, effective, safe and virtually painless wrinkle and rhytides reduction treatment.STUDY # 1
36 Sample photos: A 51 years old female Before - BaselineAfter - 3M following 8 TxSTUDY # 1
37 Sample photos: A 42 years old female Before- BaselineAfter - 3M following 8 TxSTUDY # 1
38 Sample photos: A 59 years old female Before- BaselineAfter - 3M following 8 TxSTUDY # 1
39 Sample results: A 61 years old female Before- BaselineAfter - 3M following 8 TxSTUDY # 1
40 CLINICAL EXPIRIENCE WITH A TRIPOLLAR® RADIOFREQUENCY SYSTEM FOR FACIAL AND BODY AESTHETIC TREATMENTS Dr. Alex LevenbergStudy Objective:To evaluate the safety and efficacy of the TriPollar® for non-invasive treatment of localized excess fat and facial tighteningMaterials and Methods:37 female patientsAverage of 7 treatments for wrinkles, laxity and circumference reduction on different facial and body areas.Evaluation methods:Facial results objectively analyzed with Primos 3D imaging systemPhotographs – evaluate facial resultsSTUDY # 2
41 Results:Average circumference reduction, in main body areas (abdomen, buttocks, thighs): 3.6 ± 2.4 cm (P < )Abdomen: 4.5 ± 2.7 cm, max 10.5 cmButtocks: 3.1 ± 1.7 cm, max 5 cmThighs: 2.4 ± 2.0 cm, max 6.4 cmImprovement of perioral and periorbital wrinkles was achievedBefore After 8 TxSTUDY # 2
43 OxyGeneo™ TECHNOLOGY CLINICAL STUDY Study was performed by an independent 3rd party: Physiological ModelsStudy ObjectiveTo understand the OxyGeneo™ mechanism by evaluating its effects on blood perfusion, tissue CO2 and O2 levels and the thermal effect of the treatment.Study methodBlood perfusion, tissue CO2 and O2 levels and thermal imaging profiles were measured on different body areas of 11 subjects.Base line control measurements were taken before treatment.Treatment was performed for ~10 minutes.STUDY # 1
44 OxyGeneo™ TECHNOLOGY CLINICAL EFFECT CO2 and O2 levels as measured before and after treatment:CO2 levels (in blue) returned to baseline values while the O2 (in green) levels rose above the baseline levels 15 min after treatment.STUDY # 1
45 OxyGeneo™ TECHNOLOGY CLINICAL EFFECT Increase in blood perfusion immediately after the treatment and a gradual return to base line levels.15 min after treatment the values were higher than the baseline.These parameters demonstrate an increase in flow and intensitySTUDY # 1
46 OxyGeneo™ TECHNOLOGY– NEOREVIVE CLINICAL STUDY Study method20 female volunteers, ages were included in the study.6 weekly facial treatments were conducted.Treatment was performed for ~10 minutes.The procedure was performed by a beautician and supervised by a dermatologist.The following assessments were included:Auto evaluation (questionnaires to volunteers)Evaluation Scale:RepulsiveNot satisfactoryAcceptableGoodExcellentEvaluation by professional expert (dermatologist)B&A photographsSTUDY # 2
48 NeoRevive® Results after before Enhancement of skin's pebbled appearance (elastosis).The diffuse netted pigmentation of the encircled area has almost cleared.The region looks more uniform and shiny.STUDY # 2