1. HEMOSTAZ
Yard. Doç. Dr. Murat ÖRMEN

2. SUNUM PLANI Hemostaza genel bakış Hemostatik sistemlerin bileşenleri
Primer hemostaz
Sekonder hemostaz

5. Hemotaz, kanama,tromboz animasyon

8. Coagulation Factors Fibrinogen Group Factors I, V, VIII and XIII
Prothrombin Group
Factors II, VII, IX and X
Contact Group
Factors XI, XII
Prekallikrein (Fletcher Factor)
High Molecular Weight Kininogen
(Fitzgerald Factor)

9. Thrombolytic Therapy • Anaphylaxis • GI Bleeding
• t-PA
• Streptokinase
• Urokinase
• Anaphylaxis
• GI Bleeding
• Intracranial Hemorrhage

11. Anatomy of a Platelet Dense Body ADP Serotonin ATP Calcium
Microtubular System
Glycogen
Exterior Coat
(Glycocalyx)
Mitochondria
Surface
Connecting System
Cytosol
Factor XIII
Alpha Granules
PF4 Fibrinogen
Factor V Fibronectin
Factor VIII R:ag b Thromboglobulin
(vWF)
Plasma Membrane
PF3
Dense Tubular System

12. Platelet Function Adhesion Aggregation Coagulation ADP Release A
Shape Change Release
Fibrin
Formation A B C
3 seconds
10 seconds
5 minutes
ADP
Release
Adhesion

16. PRİMER HEMOSTAZ