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HEMOSTAZ Yard. Doç. Dr. Murat ÖRMEN. SUNUM PLANI n Hemostaza genel bakış n Hemostatik sistemlerin bileşenleri n Primer hemostaz n Sekonder hemostaz.

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Presentation on theme: "HEMOSTAZ Yard. Doç. Dr. Murat ÖRMEN. SUNUM PLANI n Hemostaza genel bakış n Hemostatik sistemlerin bileşenleri n Primer hemostaz n Sekonder hemostaz."— Presentation transcript:

1 HEMOSTAZ Yard. Doç. Dr. Murat ÖRMEN

2 SUNUM PLANI n Hemostaza genel bakış n Hemostatik sistemlerin bileşenleri n Primer hemostaz n Sekonder hemostaz

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5 n Hemotaz, kanama,tromboz animasyon

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8 Coagulation Factors n Fibrinogen Group n Factors I, V, VIII and XIII n Prothrombin Group n Factors II, VII, IX and X n Contact Group n Factors XI, XII n Prekallikrein (Fletcher Factor) n High Molecular Weight Kininogen n (Fitzgerald Factor)

9 Thrombolytic Therapy t-PA Streptokinase Urokinase Anaphylaxis GI Bleeding Intracranial Hemorrhage

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11 Anatomy of a Platelet Dense Body ADPSerotonin ATPCalcium Microtubular System Glycogen Exterior Coat (Glycocalyx) Mitochondria Surface Connecting System Cytosol Factor XIII Alpha Granules PF 4 Fibrinogen Factor VFibronectin Factor VIII R:ag  Thromboglobulin (vWF) Plasma Membrane PF 3 Dense Tubular System

12 Platelet Function Aggregation Coagulation Shape Change Release Fibrin Formation A B C 3 seconds 10 seconds 5 minutes ADP Release Adhesion

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16 PRİMER HEMOSTAZ

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