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Mood & Anxiety Research in the School of Psychology Graham Davey

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1 Mood & Anxiety Research in the School of Psychology Graham Davey

2 Research Groups  Developmental & Clinical Psychology  Behavioural & Clinical Neuroscience  Cognitive Psychology  Social & Applied Psychology

3 Developmental & Clinical Psychology - Scope  The Developmental and Clinical Psychology research group has a common aim of advancing theoretical approaches to development and clinical understanding through the study of social, emotional and cognitive processes. We have a strong history of achieving new understanding by working with practitioners and service users in applied settings

4 Developmental & Clinical Psychology - Members Faculty Susan Ayers Robin Banerjee Sam Cartwright-Hatton Kate Cavanagh Graham Davey Andy Field Research Fellows Frances Meeten Mark Wright Alexandra Sawyer

5 Clinically-Related Research in the School of Psychology – Developmental & Clinical Psychology  Graham Davey: Experimental psychopathology and anxiety disorders, including conditioning models of anxiety and fear; evolutionary vs acquired models of specific phobias, the causes of perseverative psychopathologies such as pathological worrying and obsessive-compulsive checking, and the role of the disgust emotion is psychological disorders. Graham Davey  Susan Ayers: Trauma and childbirth; psychological factors in obstetrics and gynaecology; stress and coping with health events; psychological outcome following health events. Susan Ayers  Kate Cavanagh: The role of cognitive biases and reasoning processes in the emotional disorders (including psychosis) and increasing access to psychological therapies, in particular, the role of information technology and computer aided psychotherapies. Kate Cavanagh  Andy Field: Anxiety in children, the role of childhood experience in phobia acquisition; whether induced fear beliefs (i) persistent over time (ii) create cognitive biases in the processing of fear-relevant information; and (iii) are mediated by dispositional factors Andy Field

6 Child Anxiety Theory and Treatment Lab at the University of Sussex (CATTLab)  Focuses on the environmental (e.g., learning, parenting, media exposure) and individual factors (e.g. temperament, cognitive development) that affect children's developing emotional responses (especially fear and anxiety). Most of the Lab’s work explores the causal influences on children’s emotional development and how they interact with cognitive development and cognitive processes (such as learning, memory, interpretation) to create subjective feelings of fear, avoidance behaviour, physiological responses and attentional biases to threat. Recent work explores the link between cognitive and emotional development, and the emotional impact of ‘scary’ television on children

7 CATTLab Members  Andy Field (Director)  Kathryn Lester  Zoe Nightingale  External Collaborators  Suzanne Broeren (Erasmus University, Rotterdam, The Netherlands) Suzanne Broeren  Dr. Sam Cartwright-Hatton (University of Sussex)Sam Cartwright-Hatton  Dr. Cathy Creswell (University of Reading)Cathy Creswell  Dr. Ben Dyson (Ryerson University)Ben Dyson  Dr. Jorg Huijding (Erasmus University, Rotterdam, The Netherlands)Jorg Huijding  Prof. Peter Muris (Erasmus University, Rotterdam, The Netherlands)Peter Muris  Prof. Lynne Murray (University of Reading)Lynne Murray  Dr. Helena Purkis (University of Queensland)Helena Purkis  Prof. Shirley Reynolds (University of East Anglia)Shirley Reynolds

8 Behavioural & Clinical Neuroscience - Scope  The behavioural and clinical neuroscience research group at Sussex University has interests in:  the application of basic neuroscience and behavioural techniques in rodents to study the neural bases of drug addiction  the application of human psychopharmacology techniques to explore the detailed effects of drugs on human behaviour and cognition, as well as both preclinical and clinical investigations of the cognitive and other psychological deficits associated with long-term use of drugs such as ecstasy and alcohol  the neurobiology of motivation, with specialist interests in the control of ingestion  the cognitive neuroscience of human memory and attention, and especially research on deficits associated with disorders such as dementia and schizophrenia  There is a close inter-relationship between animal, human and clinical work. On the animal side, the Sussex group is one of the strongest groups in any UK university for the behavioural characterisation of transgenic mice, and enjoys collaborative links with molecular geneticists in the School of Life Sciences, with the neighbouring Sussex Centre for Neuroscience, and with the Brighton and Sussex Medical School. On both the human and animal side, the group has long-standing links with clinical health professionals across the county.  There is a dedicated unit for the laboratory study of rodents, and a human psychopharmacology laboratory, including facilities for the study of eating behaviour, and alcohol and smoking use, and incorporating a bedded unit should participants need to stay overnight.

9 Behavioural & Clinical Neuroscience - Members Faculty Dora Duka Sarah King Michael Morgan Jennifer Rusted Dai Stephens Research Fellows Leanne Trick Claire Dixon Yolanda Pena-Oliver

10 Clinically-Related Research in the School of Psychology – Behavioural & Clinical Neuroscience  Dora Duka - Alcohol and nicotine addiction: human studies of conditioning, implications for alcohol and nicotine effects; alcohol craving in humans, adaptive mechanisms, emotional and cognitive factors. Psychopharmacology of cognition: alcohol and related drugs, emotional and cognitive effects. Dora Duka  Sarah King - Molecular and behavioural effects of chronic nicotine exposure; developing novel strategies (RNAi and viral mediated gene transfer) to study aspects of drug addiction in cell culture and in vivo Sarah King  Michael Morgan - Aspects of substance misuse and dependence, from cigarette craving to persistent neuropsychological sequelae of ecstasy and other polydrug use; impulse control in adolescence and adulthood, psychopathology and substance misuse; human neuropsychopharmacology Michael Morgan  Jennifer Rusted - Psychopharmacology of human memory; prospective and action-based memory in ageing and dementia; drug models of dementia; behavioural and drug interventions for people with dementia. Jennifer Rusted  Dai Stephens - Neurobiological and behavioural mechanisms underlying drug dependence, particularly mechanisms of behavioural and brain plasticity underlying sensitisation to abused drugs. Behavioural neuroscience of GABAergic and glutamatergic systems. Dai Stephens

11 Susan Ayers  Postnatal affective disorders and memory biases (Suzanne Foley)  Screening for postnatal distress (Rose Meades)  Impact of postnatal mental health on family relationships and infant  development (Ylva Parfitt)  Use of internet self-help tools for postnatal illness (Donna Moore)  I am also working on the following using a series of UG and PG projects:  Postnatal mood, attentional biases for infant emotion recognition and the mother-baby bond.  Web-based self-help exercises for postnatal mood and PTSD

12 Robin Banerjee  Various ongoing research studies on indices of emotional functioning (including anxiety and depressive symptoms) and peer relations in children and adolescents, particularly in the context of Local Authority- funded projects on mental health, early intervention, and social and emotional learning in schools (current projects are running in Bracknell Forest, Brighton & Hove, Derby, Bridgend + Vale of Glamorgan)  Leverhulme Trust funded project on consumer culture values and children's well-being, including attention to life satisfaction, anxiety, and depressive symptoms (with Helga Dittmar at Sussex)  The self-presentational and social-cognitive dimensions of social anxiety in children with various collaborators

13 Kate Cavanagh  The role of the therapeutic relationship in computerised cognitive behavioural therapies - Kate Cavanagh, Natalie Barazzone, Rebecca Grist (University of Sussex)  Exploring Social Networks to Augment Computerised Therapies (ENACT), EPSRC funded - Shaun Lawson (PI; University of Lincoln), Conor Linehan (University of Lincon), Kevin Morgan (Univeristy of Loughborough), Niro Sarawanda (University of Lincoln), Kate Cavanagh (University of Sussex), Charlie Martin (Ultrasis plc).  The Implementation of computerised cognitive behavioural therapies in a service user- led, third sector Self Help Clinic - Kate Cavanagh, in collaboration with Nic Seccombe and Nicky Lidbetter from Self Help Services (www.selfhelpservices.org.uk)www.selfhelpservices.org.uk)  The role of attachment orientation in engagement with self-help resources - Kate Cavanagh (University of Sussex), Angela Rowe (University of Bristol), Kathy Carnelly (University of Southhampton), Rebecca Grist (University of Sussex), Jackie Nobre- Peres (University of Sussex), Vicky Alvarez-Ude (Univesrity of Sussex), Ali Argo (University of Sussex), Abi Millings(Ultrasis plc).  Project in development: The use of low-intensity therapies for common mental health problems across Sussex Partnership Trust – implementation models, decision making and effectiveness - Fergal Jones (SPT), Kate Cavanagh (University of Sussex), Monica Urbanek (Univeristy of Surrey), Herman van der Walt (University of Surrey), Peggy Papada (University of Surrey), Becky Grist (University of Sussex), Nicola Jarrett (SPT)

14 Graham Davey  Mechanisms of Catastrophic Worrying – Funded by ESRC – Research Fellow: Frances Meeten  Mood-as-input Hypothesis and Perseverative Psychopathologies  Perseverative Worrying & Information Processing Style – DPhil student: Suzanne Dash  The Bidirectionality Hypothesis: Causal Interactions Between Mood, Symptoms & Clinical Constructs – DPhil Student: Gary Britton  Embodied Cognition & Anxiety

15 Zoltan Dienes  the relationship between anxiety and sexual fantasy content.

16 Dora Duka  The effects of negative mood on addictive behaviours - BBSRC case studentship with Johnson & Johnson Pharmaceutical Research and Development (Thomas Steckler). Student: Claire Mathers  Sensitivity to threat related stimuli (emotional startle response) as a contributing factor to addiction in GABA- alpha2 risk for addiction polymorphism. MRC cluster grant (with Dai Stephens and Sarah King). Research fellow: Leanne Trick

17 Andy Field  The impact of 'scary' TV on children's emotional development and resilience.  Environmental influences on the development of fears in children.  The role of Information processing in the development and maintenance of anxiety (with Saied Rohani & Dr. Helena Purkis)

18 Sam Hutton  The effects of social anxiety on face processing  The relationship between state anxiety and pupilliary dilation  Oculomotor indices of checking behaviour

19 Michael Morgan  Pirona A, Morgan MJ An investigation of the sub-acute effects of recreational ecstasy use on neuropsychological performance, sleep and mood. J Psychopharm 24: 175–185, 2010  O. S. Findley, M. J. Morgan Social Anxiety and Problematic Alcohol Use: Investigating the Role of Drinking Motives and Alcohol Expectancies  L. Homman, M. J. Morgan The sub-acute effects of Mephadrone

20 Dai Stephens  Sensitivity to threat related stimuli (emotional startle response) as a contributing factor to addiction in GABA-alpha2 risk for addiction polymorphism. MRC cluster grant (Dai Stephens, Dora Duka and Sarah King) - Research fellow: Leanne Trick  Effects of early life stress on adult emotionality and addictive behaviours in mice with genetic manipulations of GABAA receptors - MRC Cluster grant (Dai Stephens, Dora Duka and Sarah King) - Research fellow: Claire Dixon.  Investigation of genes involved in anxiety using BxD recombinant inbred mouse strains - EU FP7 Grant "Imagen". This is a very large multicentre European study that concentrates mostly on 14-year olds who are characterised using questionnaires, psychological tests, fMRI and a genome-wide scan. The idea is to provide a data base that can be interrogated for associations, and will eventually be used to investigate mental disorders arising in early adulthood for potential predictive antecedents. Our role is to make some predictions as to which genes may be of particular interest in anxiety, impulsivity and drug abuse. (Dai Stephens) - Research Fellow: Yolanda Pena- Oliver.


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