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Karin Johansson ICT for Health DG Information Society & Media European Commission Infrastructures use, requirements & prospect in ICT for health domain.

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Presentation on theme: "Karin Johansson ICT for Health DG Information Society & Media European Commission Infrastructures use, requirements & prospect in ICT for health domain."— Presentation transcript:

1 Karin Johansson ICT for Health DG Information Society & Media European Commission Infrastructures use, requirements & prospect in ICT for health domain

2 Outline ICT for Health research activities Relevant Grid-related activities Where are we going in the short/medium term? Where do we go beyond FP7?

3 WHO ARE WE? ICT for Health (eHealth) Unit, European Commission Information Society and Media DG eHealth unit: –established in 1989 –supported to date > 450 projects worth > € 1 Billion –currently funds eHealth projects (€ 100 Million/year) The vision (since 1994): “eHealth-enabled citizen-centred care” or equivalently “eHealth-enabled continuity of care” Today’s focus –R&D: Personal Health Systems Patient Safety Modelling and Simulation of Human Physiology and Disease (Virtual Physiological Human) –Support to deployment: eHealth Action plan, Large Scale Pilots, Lead market initiative, Recommendation on Interoperability of EHRs, Communication on Telemedicine (2009)

4 Budget for research supported by the ICT for Health unit in FP7 Overall € 340 M over 4 years ( ) –Personalisation of Healthcare Personal Health Systems (PHS) € 72 M in € 63 M in 2009 –Patient safety (PS) - avoiding medical errors € 30 M in € 30 M in 2009 –Predictive Medicine – Virtual Physiological Human (VPH) Modelling/simulation of human physiology and disease € 72 M in € 5 M in € 63 M in 2010 Next work programme will cover and will be published on CORDIS in Oct-Nov 2010.

5 Outline ICT for Health research activities Relevant Grid-related activities Where are we going in the short/medium term? Where do we go beyond FP7?

6 Where are Grid activities most relevant? VPH –Need for data capacity originates from biomedical informatics roots –Huge demand on Data storage/management Computing power Patient Safety (PS) –Early detection of public health events –Re-use of EHR data for research purposes

7 The Virtual Physiological Human is a methodological and technological framework that once established will enable the investigation of the human body as a single complex system. One of the 12 pioneer projects in FP6, The VPH research roadmap developed by project STEP in 2007: - Personalised (patient-specific) healthcare solutions - Early diagnostics & predictive medicine - Understanding diseases for the first time across several biological levels Based on the ideas of the International Physiome project The Virtual Physiological Human (VPH) concept

8 Virtual Physiological Human: a schematic picture Knowledge of biological and physiological pathways, processes etc Computational resources Data access Data processing Modelling Construction and/or refinement of models on different temporal and spatial scales Integration of models Multiscale model verification Health care professionals Hospital Patient Specific Data -omics imaging clinical pharma Data management Prediction, Early Diagnosis, Treatment Application Clinical validation Patient

9 Technical focus: Patient-specific computational modelling and simulation of organs targeting specific clinical needs. Data integration and new knowledge extraction. Clinical focus: Simulation environments for surgery training, planning and intervention. Prediction of disease or early diagnosis. Simulation and assessment of the efficacy and safety of specific drugs. First VPH Call: FP7 call 2

10 Results of the 1st VPH call: 15 FP7 projects Networking NoE Osteoporosis IP Alzheimer's/ BM & diagnosis STREP Heart /CV disease STREP Cancer STREP Liver surgery STREP Heart/ LVD surgery STREP Oral cancer/ BM D&T STREP CV/ Atheroschlerosis IP Breast cancer/ diagnosis STREP Vascular/ AVF & haemodialysis STREP Liver cancer/RFA therapy STREP Security and Privacy in VPH CA Grid access CA Heart /CV disease STREP Industry Clinics Reproduction from VPH NoE Parallel VPH projects

11 Results of the 1st VPH call: 15 FP7 projects Networking NoE Osteoporosis IP Alzheimer's/ BM & diagnosis STREP Heart /CV disease STREP Cancer STREP Liver surgery STREP Heart/ LVD surgery STREP Oral cancer/ BM D&T STREP CV/ Atheroschlerosis IP Breast cancer/ diagnosis STREP Vascular/ AVF & haemodialysis STREP Liver cancer/RFA therapy STREP Security and Privacy in VPH CA Grid access CA Heart /CV disease STREP Industry Clinics Reproduction from VPH NoE Parallel VPH projects

12 Second VPH call: FP7 call 4 International Cooperation on VPH Focus : Interoperability (interfaces databases, web services, mark-up languages, meta-data, ontologies) Tools and services for global cooperation (for modelling/simulation, curated models, interconnected libraries) International validation environment (joint verification of clinical relevance of models) Budget: 5M€ Results: 5 proposals selected, all of which include international partners.

13 ICT for Patient safety Focus of Call: ICT for safer surgery ICT for integration of clinical research and clinical care ICT-enabled early detection of public health events Budget : 30M€ Results: 9 retained (2 IPs, 6 STREPs, 1 SA) But: Public health policy is mainly the responsibility of Directorate General Health and Consumer (DG SANCO) projects

14 DEISA/PRACE Symposium – Amsterdam, NL 14 eInfrastructure: the European HPC Service PRACE National/Regional DEISA and EGI National Local

15 DEISA/PRACE Symposium – Amsterdam, NL 15 DEISA: ‘virtual’ HPC services  12 sites in 7 countries connected at 10 Gb/s  Over 22,000 CPUs with an aggregated peak performance of close to 1 Peta flops  Running larger parallel applications in individual sites  Enabling workflow applications with grid technologies (UNICORE)  Providing a global data management service  Extreme Computing Initiative

16 NGI-E NGI-I NGI- Nordic States NGI-D NGI-F NGI-UK NGI-IRL NGI-GR NGI-P NGI-CZ NGI-A NGI-NL NGI-PO NGI-B NGI-SK Coordinating entity (EGI) Key elements of new scheme:  Coordination/pooling of National and European funding for sustainable service provision and for more efficient planning of investments  Service provisioning beyond project cycles  One-stop-shop service provisioning (including training) to users who want to access grid-based resources EGI_DS (Design study) establishing new organisational model for sustainable grid service provisioning

17 DEISA/PRACE Symposium – Amsterdam, NL 17 PRACE: preparatory phase  Late 2009: 1PF in the top 5  Late 2010: 2 PF in the top 5; 1PF in the top 10  2011: 3 PF in the top 5; 2 PF in the top 10  2020: an exaflop in the top 5

18 Outline ICT for Health research activities Relevant Grid-related activities Where are we going in the short/medium term? Where do we go beyond FP7?

19 Virtual Physiological Human future activities Keep the overall VPH goals:  Early diagnostics & Predictive medicine  Personalised (Patient-specific) healthcare solution By means of:  Modelling & simulation of human physiology and disease- related processes  Add emphasis on tools/infrastructure for biomedical researchers VPH in 2010  Call 6 expected to open November 2009 and to close in April 2010  Budget 63M€

20 VPH infrastructure needs Demand for:  Data management  Computing power Requirements (coupling research activities with applications)  No longer sufficient to make technological advances within the GRID research  Engage users  Usability/user accessibility  Routinely used in applied research in other domains (VPH and others)  Develop culture of sharing

21 VPH Call 6 Focus a): Patient-specific computer based models and simulation  Multiscale models & simulation of organs/systems targeting specific clinical needs.  Better understanding of the functioning of the organs and their pathologies aiming at prediction/early diagnosis. Emphasis on:  Integration of existing models  Clinical benefits demonstrated  Data acquisition, medical, clinical, bio research (if needed) < 25%  Access to external computing facilities supported

22 VPH call 6 Focus b): ICT tools, services and infrastructures for bio- medical researchers to support at least 2 of the 3 activities: 1.Share data and knowledge 2.Jointly develop and share models/simulators 3.Create collaborative environments  Interface to access to resources like Grid/HPC infrastructures  Ability to interface with existing medical research infrastructure  Complement/compatible with existing methods/standards to be suggested by VPH-NoE

23 VPH Call 6 Focus c) & d) Evaluation and assessment of VPH Projects w.r.t. optimal use and contribution of  Shared tools/infrastructure  Clinical achievements  Market potential/ penetration Observatory on achievements and evolution of the broader BMI field (e.g. bioinformatics, Medical informatics, neuro-informatics):  Facilitate communication between projects  Dissemination and training Aim at:  Sustaining cross collaboration among different fields  Build on related NoEs.

24 Outline ICT for Health research activities Relevant Grid-related activities Where are we going in the short/medium term? Where do we go beyond FP7?

25 Support projects cutting across research, innovation and deployment As part of COM(2009)116 on « A strategy for ICT R&D Innovation in Europe », the Commission proposed Limited set of project cases that cut across the innovation chain Each project focused on specific characteristics of a pan-European service infrastructures addressing a specific societal goal To speed up the achievement of results there is a need to orchestrate efforts across research, innovation and deployment –e.g. multi-financed large-scale initiatives in FP and CIP and national and regional actions including procurement of R&D and innovation

26 Example projects cutting across research, innovation and deployment European Large Scale Action in ICT for Health ICT service infrastructure for personal healthcare –Specific societal goal: better integrated care and management of chronic diseases at the point of need; continuous and personalised care … –Specific characteristics: accuracy of measurements, remote control by health professionals, self-monitoring …

27 Contact persons DG Information Society and Media Unit “ICT for Health” Virtual Physiological Human team: Joël Bacquet Karin Johansson Amalia Vlad eInfrastructure team: Enric Mitjana Maria Ramalho Bernhard Fabianek Contact person for EGI-related part of FP7-INFRASTRUCTURES : Monika Kacik


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