1. The author has a financial interest in the matter under presentation Dr. Rupal Shah, New Vision Laser Centers, India

2. Uses only the femtosecond laser for completing the entire LASIK procedure No need for an excimer laser Possible only with the VisuMax Laser from Carl Zeiss Two Procedures FLEx=Femtosecond Lenticule Extraction SMILE=Small Incision Lenticule Extraction

3. All-Femto Lasik Integrated Solution Benefits and Advantages Advantages for the patient Vision correction w/o corneal ablation Result quality independent of external conditions High refractive correction with less induced aberration Fast single-step treatment Short period of stress and fear No need to change stations Potential for minimal-invasive procedure Better and faster healing (small incisions) Preserved biomechanical stability of the cornea Potential for correction of higher myopes Lower incidence of Dry-Eye syndrome (to be proven) Advantages for the surgeon Differentiation from other LVC providers Uniqueness of AIO procedure (marketing, positioning) Workflow improvements Fast bilateral treatment w/o need to change to excimer higher patient throughput Less space requirement Increased profitability Premium procedure provides higher margin potential (ex.: Intralase, Wavefront) Minimal-invasive treatment may increase demand Only one laser, with the investment, consumables and service costs for only laser

4. 683 eyes treated between Aug 2008 and February 2010 Includes eyes treated with both FLEx and SMILE All consecutive eyes- All eyes treated have been included Video Illustrates technique of All in One (AiO) Femtosecond Laser Refractive Surgery

5. Subject Demographics MeanRange Age25 y18 y to 50y MR SEQ-4.56 D ± 2.04 D-0.75 D to -10.38 D MR Sphere-4.22 D ± 1.95 D-0.50 D to -10.00 D MR Cylinder-0.68 D ± 0.72 Dup to -4.50 D Pre-operative: 683 eligible eyes (339 OD, 344 OS) 429 female eyes, 254 male eyes

6. Postoperative Results MeanRange MR SEQ0.00 D ± 0.26 D1.00 D to -1.25 D MR Sphere0.00 D ± 0.21 D1.00 D to -1.25 D MR Cylinder-0.10 D ± 0.26 Dup to -1.75 D 6 month423 eyes

7. AiO Safety Change in CDVA @3 month 92% unchanged/gained

8. AiO Stability Achieved correction (MR SEQ) over time Highly stable refraction over time!

9. AiO Refractive Outcome MR SEQ Percent within Attempted @1w and @6m 1 week (639) 6 month (423) High predictability for early and late follow-ups!

10. AiO Refractive Outcome MR SEQ Percent within Attempted @1w 99% ± 1.00 D @3m 100% ± 1.00 D

11. Only 94% are 20/25 or better preOP

12. AiO-Astigmatism Correction Normalized Double Angle Minus Cylinder – Scatter Plot only eyes with myopic astigmatism preOP (485 eyes with myopic astigmatism) High predictability in cylinder correction after 1 week! 1 week (460 eyes with myopic astigmatism)