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Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 1.

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Presentation on theme: "Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 1."— Presentation transcript:

1 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 1

2 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 2 Content Terminology What action potential really means Where we can find it Neurones Networks of neurones Processing of information

3 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 2 A temporary reversal in the potential difference across a plasma membrane that occurs when a cell has been activated by a stimulus. Action potential definition

4 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 2 Potential energy = potential to deliver work U = m x g x h

5 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 2 Tsunami

6 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 2 U = Q 1 x Q 2 / r = 1.5 V ~ 220 V U … voltage Q 1 … charge Q 2 … charge r … distance

7 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page Electric potential is a voltage that we measure with a voltmeter.

8 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page Electric potential is a voltage that we measure with a voltmeter.

9 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page Electric potential is a voltage that we measure with a voltmeter.

10 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page Electric current is a movement of free electrons.

11 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page Ions exert force on free electrons which move the voltmeter pointer.

12 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 2 + -

13 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 2

14 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 2 Where can we see action potential? Neurones Pacemaker cells Neuromuscular junction

15 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 2

16 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 2 Action potential

17 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 2 Conduction in myelinated vs. non-myel. neurones 10 – 120 m/s m/s

18 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 2 Saltatory conduction

19 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 2 5 m 18 m

20 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 2

21 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 2 Synaptic transmission

22 Physiology, 2 nd Faculty of Medicine, Charles University Copyright © 2010 Ludek Nerad Introduction To Action Potential Physiology page 2


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