1. Review Article Acute Pulmonary Embolism
Victor F. Tapson, M.D.
N Engl J Med
Volume 358(10):
March 6, 2008

2. Summary
Acute pulmonary embolism may occur rapidly and unpredictably and may be difficult to diagnose.
Treatment can reduce mortality, and appropriate primary prophylaxis is usually effective.
This review focuses on the pathogenesis, diagnosis, and treatment of acute pulmonary embolism of thrombotic origin.

3. Outline Epidemiology and Pathophysiology Risk Factors
Acquired Risk Factors
Genetic Disorders and Thromboembolic Risk
Diagnostic Approaches
Clinical Manifestations
Preliminary Laboratory Testing and Pretest Probability
Imaging Studies
Treatment
Anticoagulation
Placement of a Vena Caval Filter
Treatment of Massive Pulmonary Embolism
Complications of Thrombolytic Therapy
Prognosis
Prevention
Pregnancy and Acute Pulmonary Embolism
Conclusions

4. Pathophysiology of Pulmonary Embolism
Tapson V. N Engl J Med 2008;358:

5. Risk Factors for Venous Thromboembolism
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6. Clinical Prediction Scores for Suspected Acute Pulmonary Embolism
Tapson V. N Engl J Med 2008;358:

7. Contrast-Enhanced CT Angiograms Showing Acute Pulmonary Embolism
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8. Diagnostic Approach to Suspected Acute Pulmonary Embolism
Tapson V. N Engl J Med 2008;358:

9. Treatment of Acute Pulmonary Embolism
Tapson V. N Engl J Med 2008;358: