1. DEPARTMENT OF ENVIRONMENTAL SCIENCE FACULTY OF SCIENCE Mark Huijbregts and Aafke Schipper Environmental Sciences

2. Radboud University Nijmegen Environmental Sciences Introduction Mark Huijbregts Assistent Professor, Department Environmental Science, Radboud University, Nijmegen Field of Expertsise: Risk Assessment of chemicals and Life Cycle Assessment of products Aafke Schipper Postdoc, Department Environmental Science, Radboud University, Nijmegen Field of Expertise: Multistress assessment in river ecosystems

3. Radboud University Nijmegen Environmental Sciences Human and Environmental Risk Assessment (HERA): Substances StaffDr. Ad Ragas, Dr. Mark Huijbregts Prof. Dik v.d. Meent/Ton Breure (RIVM), Prof. Jan Hendriks AimEnvironmental risk management Topicsrisk assessment, uncertainty analysis critical body burdens, valuation CO 2, CH 4, N, PCB, Cd, H + …

4. Radboud University Nijmegen Environmental Sciences Nature and Water Management (NWM): Rivers and Estuaries StaffDr. Rob Leuven, Dr. Rob Lenders Dr. Marieke van Katwijk, Prof. Peter Herman (NIOO), Prof. Jan Hendriks AimIntegrated river-coastal management TopicsDevelopment and restoration, rivers- estuaries, multi-stress, sea grass meadows, eco-engineering, bio-invasions

5. Radboud University Nijmegen Environmental Sciences Uncertainty in a risk assessment framework 1. Expertise RU - EUTGD spreadsheet, Simplebox - Monte Carlo simulation 1-4 - Comparison with field data 5-8 - Uncertainty versus variability 2,9 2. Contribution RU - Assessment of uncertainty in environmental risk outcomes due to uncertainties in the new QSAR regression equations - Identifying dominant sources of uncertainties in the probabilistic analysis - Comparison with field data? References 1. Roelofs et al. 2003. ETC 22 (6): 1387-1393. 2. Hauck et al. Chemosphere 72 (6): 959-967. 3. Harbers et al. 2006. EST 40 (5): 1573-1580. 4. Henning-de Jong et al. 2008. ETC 27 (3):737-745. 5. Smitkova et al. 2005. SAR QSAR Research 16 (5): 483–493. 6. Hauck et al. 2007. EST 41 (8): 2738-2744. 7 Hendriks et al. 2007. Chemosphere 70 (1): 46-56. 8. De Vos et al. 2008. Chemosphere 70 (10): 1766-1773. 9. Ragas et al. 2009. IEAM 5 (1): 27–37.

6. Radboud University Nijmegen Environmental Sciences 1. Expertise RU - Mechanistic population/ecosystem models 1-3 - Multivariate statistical analysis 4 - Valuation from the life cycle assessment of products 2. Contribution RU - Quantifying effects of toxicants on ecosystem services - mechanistic versus statistical - various geographical scales - comparison with other stressors - Value of the ecosystem services affected - Application to the chemical classes included in CADASTER References 1. Breure et al. 2008. Science of the Total Environment 406 (3): 530-536. 2. Hendriks, 2007. Ecological Modelling 2007; 205: 196-208. 3 Hendriks and Enserink, 1996. Ecological Modelling 88 (1-3): 247-262. 4. Schipper et al. 2008. Environmental Pollution 151: 17-26. Valuation of substitution of chemicals