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Agitated Patients: Clinical Overview and Problem Definition

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1 Agitated Patients: Clinical Overview and Problem Definition
FERNE/MEMC Session: Agitated Patients: Clinical Overview and Problem Definition Leslie Zun, MD, MBA, FAAEM Professor and Chair Rosalind Franklin University/Chicago Medical School Department of Emergency Medicine Mount Sinai Hospital Les Zun, MD, MBA, FAAEM

2 Disclosures Alexza Pharmaceuticals Sanofi-Aventis
FERNE/MEMC Session: Disclosures Alexza Pharmaceuticals Sanofi-Aventis Les Zun, MD, MBA, FAAEM

3 Agitation Definition Escalation Signs of agitation
Excessive verbal and/or motor behavior Escalation Verbal Physical Violence Signs of agitation Pacing Irritable Affective liability Verbal outbursts Clenching fists or jaws Threatening or destructive behavior Slamming or banging objects Les Zun, MD, MBA, FAAEM

4 Prevalence Psychiatric patients in US Prevalence of agitation in US
4.3 million ED US visits per year 5.4% of ED patients Prevalence of agitation in US Up to 1.7 million ED visits Incidence of violence in US 50% of healthcare providers in their career 51% of MDs and 67% of nurses in ED were physically assaulted in the last 6 months 2/3 containment and 1/3 random Les Zun, MD, MBA, FAAEM

5 Etiology Drug and alcohol intoxication or withdrawal Medical
Hypoglycemia Hyperthyroidism Delirium Dementia Head Trauma Temporal Lobe Epilepsy Psychiatric Schizophrenia Mania Agitated depression Personality disorder – Antisocial, borderline PT Akathisia Les Zun, MD, MBA, FAAEM

6 Etiology Drug and alcohol intoxication or withdrawal Medical
Hypoglycemia Hyperthyroidism Delirium Dementia Head Trauma Temporal Lobe Epilepsy Psychiatric Schizophrenia Mania Agitated depression Personality disorder – Antisocial, borderline PTSD Akathisia Etiology Les Zun, MD, MBA, FAAEM

7 Evaluation Differentiate medical from psychiatric etiology
Age Prior history Vital signs Physical examination findings Focal neurologic findings Glucose Oxygenation Laboratories? Radiography-CT Scan Delirium vs. dementia Les Zun, MD, MBA, FAAEM

8 Delirium vs. dementia Delirium Dementia Onset Acute Slow Awareness
Reduced Clear Alertness Fluctuates Normal Orientation Impaired Memory Perception Hallucinations Intact Thinking Disorganized Vague Language Word finding difficulty Les Zun, MD, MBA, FAAEM

9 Patient Identification Citrone, L, Volavka: Violent patients in the emergency setting. Psych Clinic NA 1999;22: High risk Schizophrenia + substance abuse + medication non-compliance > Schizophrenia >Affective disorders Factors that precipitate violent behavior alone or in combination Comorbid substance abuse, dependence or intoxication Hallucinations or delusions Poor impulse control Character pathology Chaotic environment Les Zun, MD, MBA, FAAEM

10 Chaotic Environment Level of Agitation From ED Arrival Zun, LS and Downey, LA: Level of agitation of patients presenting to an emergency department. Primary Care Companion J Clin Psychiatry 2008;10: Les Zun, MD, MBA, FAAEM

11 Progression Do all patients progress? Which patients progress?
How to prevent progression? Les Zun, MD, MBA, FAAEM

12 Reason to treat agitated patients
Prevent violence Up to 75% ED staff victims of violence Better able to assess the patient Binder, Rl, McNeil, DE: Contemporary practices in managing acutely violent patients in 20 psychiatric emergency rooms. Psych Services 1999;50: 17 of 20 medical directors stated that the patients are so agitated that it is difficult to get vital signs. 14 of 20 said the protocol was to physically restrain patients and medicate them prior to a medical work-up Begin therapeutic process Fishkind, AB: Agitation II: De-escalation of the aggressive patient and avoiding coercion. Emergency Psychiatry, 2008. Collaborative interactions Elicit information Patients say all they want Include patients in planning Empathize Les Zun, MD, MBA, FAAEM

13 Treatment Treat medical condition Reduce stimulation
Verbal de-escalation - “Talk em down” Alternatives to restraints Restrain Physical Chemical Combination Seclusion Les Zun, MD, MBA, FAAEM

14 Prevent Violence Brasic, JR, Fogel, D:Clinical safety
Prevent Violence Brasic, JR, Fogel, D:Clinical safety. Psych Clinic NA 1999;22: Identify violent patients Search patients for weapons Use a comprehensive, collaborative approach to the patient Strategies Administrative Behavioral Environmental Les Zun, MD, MBA, FAAEM

15 Prevent Violence-Strategies Brasic, JR, Fogel, D:Clinical safety
Prevent Violence-Strategies Brasic, JR, Fogel, D:Clinical safety. Psych Clinic NA 1999;22: Administrative Gangs involvement Evacuation plan Staff training Behavioral Be direct, polite and respectful Keep close to open exit Listen to patient Use non-threatening speech and behavior Security alert Environmental Monitor rooms Well trained security presence – Clinical training programs eg CPI Panic alerts Les Zun, MD, MBA, FAAEM

16 Agitated Patients: Clinical Overview and Problem Definition Summary
Agitation and violence common in ED Evaluate for possible treatable conditions Apply techniques to reduce agitation Identify agitated patients Be pre-emptive Utilize appropriate resources Employ strategies to prevent violence Search all patients Isolate and observe Les Zun, MD, MBA, FAAEM


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