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Table S1: Characteristics of the cancer patients

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1 Table S1: Characteristics of the cancer patients
Chen et al, Supplementary Material Table S1: Characteristics of the cancer patients Cancer types n Age Range Median Gender Stages Breast cancer 40 25-91 57 F:40 I:4 II:18 III:18 Colon cancer 50 41 -90 51 M:32 A:2 F:18 B:25 C:23

2 Chen et al, Supplementary Material
Table S2: Serum concentrations of galectins and cytokines in human breast and colon cancer patients Median (ng/ml) Range (ng/ml) 5th Percentile 95th Percentile Breast cancer patients (N=40) Gal-2 34.1 893.2 6.1 240.1 Gal-4 13.7 409.7 0.03 331.4 Gal-8 16.2 270.9 4.7 233.2 G-CSF 30.1 0.9 1520.5 IL-6 15.1 4680.1 2.3 361.3 GROα/CXCL-1 0.3 13.3 0.02 9.6 MCP-1/CCL-2 0.6 2.8 0.15 2.0 Colon cancer patients (n=50) 30.0 1151.0 12.1 626.5 48.7 583.2 1.6 455.4 17.7 466.4 5.6 178.2 30.4 2925.7 15.0 827.9 5.1 285.8 72.0 4.0 59.1 1.9 9.8 1.8 11.8 7.3

3 A B C D Chen et al, Supplementary Material
Fig S1. Recombinant human galectin-2, -4 an d-8 induce cytokine secretion from mouse vein endothelial cells. C57BL/6 mouse vein endothelial cells (MVECs) (from Cell Biologics, IL) were treated with 1.5μg/ml recombinant human galectin-2, -4, -8 or BSA for 24 hr at 370C before the G-CSF (A), IL-6 (B), GROα ( C) and MCP-1 (D) levels in the culture media were determined by individual mouse cytokine ELISA. The data are expressed as percentage compared with BSA-treated controls. *p<0.05, **p<0.01 (ANOVA, Bonferroni).

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