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Prognostic Impact of Fibroblast Growth Factor 2 in Non-small Cell Lung Cancer: Coexpression with VEGFR-3 and PDGF-B Predicts Poor Survival  Tom Donnem,

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Presentation on theme: "Prognostic Impact of Fibroblast Growth Factor 2 in Non-small Cell Lung Cancer: Coexpression with VEGFR-3 and PDGF-B Predicts Poor Survival  Tom Donnem,"— Presentation transcript:

1 Prognostic Impact of Fibroblast Growth Factor 2 in Non-small Cell Lung Cancer: Coexpression with VEGFR-3 and PDGF-B Predicts Poor Survival  Tom Donnem, MD, Khalid Al-Shibli, MD, Samer Al-Saad, MD, Lill-Tove Busund, MD, PhD, Roy M. Bremnes, MD, PhD  Journal of Thoracic Oncology  Volume 4, Issue 5, Pages (May 2009) DOI: /JTO.0b013e31819f2e38 Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Immunohistochemical analysis of tissue microarray block (TMA) of non-small cell lung cancer (NSCLC) representing different score for tumor cell basic fibroblast growth factor (FGF2) and stromal FGF2; (A) Tumor cell FGF2 score 1; (B) Tumor cell FGF2 score 3; (C) Stromal FGF2 low score (density 1, intensity 0); (D) Stromal FGF2 high score (density 3, intensity 3). Journal of Thoracic Oncology 2009 4, DOI: ( /JTO.0b013e31819f2e38) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Disease-specific survival curves according to; (A) tumor cell basic growth factor (FGF2) expression; (B) stromal FGF2 expression. Journal of Thoracic Oncology 2009 4, DOI: ( /JTO.0b013e31819f2e38) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 Disease-specific survival curves according to; (A) coexpression basic growth factor (FGF2) and vascular endothelial growth factor receptor (VEGFR)-3; (B) coexpression fibroblast growth factor receptor (FGFR)-1 and platelet-derived growth factor (PDGF)-B. Journal of Thoracic Oncology 2009 4, DOI: ( /JTO.0b013e31819f2e38) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

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