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Volume 24, Issue 6, (December 2016)

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1 Volume 24, Issue 6, (December 2016)
Indoleamine 2,3-Dioxygenase-Expressing Aortic Plasmacytoid Dendritic Cells Protect against Atherosclerosis by Induction of Regulatory T Cells  Tae Jin Yun, Jun Seong Lee, Kawthar Machmach, Dahee Shim, Junhee Choi, Young Jin Wi, Hyung Seok Jang, In-Hyuk Jung, Kyeongdae Kim, Won Kee Yoon, Mohammad Alam Miah, Bin Li, Jinsam Chang, Mariana G. Bego, Tram N.Q. Pham, Jakob Loschko, Jörg Hermann Fritz, Anne B. Krug, Seung-Pyo Lee, Tibor Keler, Jean V. Guimond, Elie Haddad, Eric A. Cohen, Martin G. Sirois, Ismail El-Hamamsy, Marco Colonna, Goo Taeg Oh, Jae-Hoon Choi, Cheolho Cheong  Cell Metabolism  Volume 24, Issue 6, (December 2016) DOI: /j.cmet Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 Prolonged Depletion of Splenic pDCs in Ldlr−/− Mice Reconstituted with Bone Marrow Cells of BDCA2-DTR Mice (A–D) Lethally irradiated Ldlr−/− mice reconstituted with BM cells of BDCA2-DTR mice were fed WD and injected i.p. with PBS or 0.5 μg DT weekly for 12 weeks (A and B), or were fed WD for 12 weeks and injected i.p. with PBS or 0.5 μg DT weekly only for the last 6 weeks (C and D). (A) Enumeration of pDCs in spleen (per 1 × 106 CD45+ cells). Bars indicate mean; n ≥ 10. (B) Representative FACS plots of pDCs in spleen. Numbers in plots indicate the percentages of pDCs. (C) Enumeration of pDCs in spleen (per 1 × 106 CD45+ cells). Bars indicate mean; n ≥ 8. (D) Representative FACS plots of pDCs in spleen. Numbers in plots indicate the percentages of pDCs. Cell Metabolism  , DOI: ( /j.cmet ) Copyright © 2016 Elsevier Inc. Terms and Conditions


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