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Jean-Claude Davin, Ineke J. Ten Berge, Jan J. Weening 

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Presentation on theme: "Jean-Claude Davin, Ineke J. Ten Berge, Jan J. Weening "— Presentation transcript:

1 What is the difference between IgA nephropathy and Henoch-Schönlein purpura nephritis? 
Jean-Claude Davin, Ineke J. Ten Berge, Jan J. Weening  Kidney International  Volume 59, Issue 3, Pages (March 2001) DOI: /j x Copyright © 2001 International Society of Nephrology Terms and Conditions

2 Figure 1 Relationship between initial clinical signs and risk of chronic renal failure in Henoch-Schönlein purpura nephritis (HSPN)25. Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions

3 Figure 2 Immunofluorescence micrograph of a glomerulus from a patient with IgA nephropathy (IgAN) stained for the presence of IgA. A coarsely granular, mesangial staining pattern can be observed (×250). Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions

4 Figure 3 Immunofluorescence micrograph of a glomerulus from a patient with HSP nephropathy stained for the presence of IgA. A granular, partial capillary, partial mesangial staining pattern can be observed (×200). Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions

5 Figure 4 Light micrograph of a glomerulus from the same patient with IgAN as in Figure 2 showing mesangial expansion caused by accumulation of extracellular matrix and hypercellularity. Methenamine silver (×250). Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions

6 Figure 5 Light micrograph of a glomerulus from the same patient with HSP nephropathy as in Figure 3 with influx of neutrophils, fibrinoid necrosis, and intracapillary and extracapillary proliferation, a pattern typical for systemic vasculitis. Methenamine silver (×200). Kidney International  , DOI: ( /j x) Copyright © 2001 International Society of Nephrology Terms and Conditions


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