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DNA Polymerase III: Running Rings around the Fork

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Presentation on theme: "DNA Polymerase III: Running Rings around the Fork"— Presentation transcript:

1 DNA Polymerase III: Running Rings around the Fork
Daniel R. Herendeen, Thomas J. Kelly  Cell  Volume 84, Issue 1, Pages 5-8 (January 1996) DOI: /S (00)

2 Figure 1 The Pol III* Subassembly of DNA Pol III Holoenzyme
Adapted from Onrust et al Cell  , 5-8DOI: ( /S (00) )

3 Figure 2 Synthesis of Okazaki Fragments by Pol III Holoenzyme during Lagging Strand Replication For simplicity, the diagram shows only pol III core and the γ complex. Other components of the pol III holoenzyme, including the τ subunit and the second pol III core molecule that mediates leading strand synthesis, are omitted. The timing of ATP hydrolysis is speculative. Cell  , 5-8DOI: ( /S (00) )


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