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Growth factors and experimental arterial grafts

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Presentation on theme: "Growth factors and experimental arterial grafts"— Presentation transcript:

1 Growth factors and experimental arterial grafts
Antonio V. Sterpetti, MD, FACS, FRCS, Sandro Lepidi, MD, Valeria Borrelli, PhD, Luca Di Marzo, MD, Paolo Sapienza, MD, Alessandra Cucina, PhD, Marco Ventura, MD  Journal of Vascular Surgery  Volume 64, Issue 5, Pages (November 2016) DOI: /j.jvs Copyright © 2015 Society for Vascular Surgery Terms and Conditions

2 Fig 1 A, Histochemical localization of basic fibroblast growth factor (bFGF) in arterial vein grafts explanted 4 weeks after surgery (transverse section): localization of bFGF in smooth muscle cells which form the area of myointimal hyperplasia (MH; original magnification ×400), L, Lumen. B, Histochemical localization of platelet-derived growth factor (PDGF) in arterial vein grafts explanted 4 weeks after surgery (transverse section): localization of PDGF in smooth muscle cells which form the area of MH (original magnification ×400). Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

3 Fig 2 Histochemistry for interleukin (IL)-1 in arterial isografts (left) and arterial allografts (right) explanted 4 weeks after surgery (transverse sections). No detectable localization of IL-1 in isografts (left). Evident localization of IL-1 in the area of myointimal hyperplasia (MH) in aortic allografts (original magnification ×200). L, Lumen. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

4 Fig 3 Histochemistry for tumor necrosis factor (TNF)-α in arterial isografts (left) and arterial allografts (right) explanted 4 weeks after surgery (transverse sections). No detectable localization of TNF-α in isografts (left). Evident localization of TNF-α in the area of myoinitmal hyperplasia in aortic allografts (original magnification ×200). L, Lumen. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

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