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Perioperative Statin Therapy for Patients Undergoing Coronary Artery Bypass Grafting  Amr F. Barakat, MD, Marwan Saad, MD, PhD, Ahmed Abuzaid, MD, Amgad.

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Presentation on theme: "Perioperative Statin Therapy for Patients Undergoing Coronary Artery Bypass Grafting  Amr F. Barakat, MD, Marwan Saad, MD, PhD, Ahmed Abuzaid, MD, Amgad."— Presentation transcript:

1 Perioperative Statin Therapy for Patients Undergoing Coronary Artery Bypass Grafting 
Amr F. Barakat, MD, Marwan Saad, MD, PhD, Ahmed Abuzaid, MD, Amgad Mentias, MD, Ahmed Mahmoud, MD, Islam Y. Elgendy, MD  The Annals of Thoracic Surgery  Volume 101, Issue 2, Pages (February 2016) DOI: /j.athoracsur Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Pleiotropic effects of statins. (bFGF = basic fibroblast growth factor; CRP = C-reactive protein; eNOS = endothelial NO synthase; ET-1 = endothelin-1; IL-6 = interleukin 6; LDL = low-density lipoprotein; NO = nitric oxide; PDGF = platelet-derived growth factor; TNF-α = tumor necrosis factor alpha; TXA2 = thromboxane A2.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 The overall summary estimates for various outcomes as reported by multiple meta-analyses conducted on preoperative statin therapy (PST) before coronary artery bypass grafting. *Analysis included all cardiac surgery and not isolated coronary artery bypass grafting. (AKI = acute kidney injury.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

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