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Published byJean-Baptiste Joly Modified over 5 years ago
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T regulatory cells turn on T regulatory cells
by David W. Scott Blood Volume 114(19): November 5, 2009 ©2009 by American Society of Hematology
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Regulatory CD4 T cells are generated in a FoxP3 transgenic mouse injected with an immunogenic FVIII vector. Regulatory CD4 T cells are generated in a FoxP3 transgenic mouse injected with an immunogenic FVIII vector. When transferred to a naive recipient, these CD4 cells suppress the response to FVIII and generate Tregs from the host. Professional illustration by Kenneth X. Probst. David W. Scott Blood 2009;114: ©2009 by American Society of Hematology
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