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14-3-3 binding sites 58 of the 473 unambiguously assigned phosphorylation sites are predicted by Scansite to be sites for 14-3-3 binding. 50 of these correspond.

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Presentation on theme: "14-3-3 binding sites 58 of the 473 unambiguously assigned phosphorylation sites are predicted by Scansite to be sites for 14-3-3 binding. 50 of these correspond."— Presentation transcript:

1 binding sites 58 of the 473 unambiguously assigned phosphorylation sites are predicted by Scansite to be sites for binding. 50 of these correspond to the three consensus motifs in this table (A, B, and C), and 44 of these are located in regions of disorder as assessed by PONDR analysis. binding sites 58 of the 473 unambiguously assigned phosphorylation sites are predicted by Scansite to be sites for binding. 50 of these correspond to the three consensus motifs in this table (A, B, and C), and 44 of these are located in regions of disorder as assessed by PONDR analysis. The Score column is the Scansite score for sites to be binding sites, and the most likely kinase to act on each site (as assessed by Scansite) is shown with associated scores in parentheses. The PONDR column indicates whether each site is predicted to be in a disordered (Disord) or ordered (Order) sequence. PKC, protein kinase C; PKC e, PKC ε; ATM, ataxia telangiectasia mutated. Mark O. Collins et al. Mol Cell Proteomics 2008;7: © 2008 The American Society for Biochemistry and Molecular Biology


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