1. Nat. Rev. Neurol. doi:10.1038/nrneurol.2018.14
Figure 3 Age-related white matter lesions and cerebrovascular disease lesions
Figure 3 | Age-related white matter lesions and cerebrovascular disease lesions. a | Axial fluid-attenuated inversion recovery (FLAIR) brain MRI showing periventricular pencil-thin lining hyperintensities and bilateral, symmetrical caps lining the frontal horns of the lateral ventricles (arrows), features that are commonly seen in normal ageing. b | Microbleeds associated with small vessel disease (SVD), depicted in an axial gradient-echo T2*-weighted image as rounded hypointensities in the basal ganglia (arrows) and the cortex. c | An axial FLAIR image showing periventricular white matter hyperintensities that spare the U-fibres and lacunar infarcts in the deep white matter and grey matter (arrow), associated with SVD. d | Temporal pole white matter hyperintensities (arrow) associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), shown in an axial FLAIR image. e | Hyperintense white matter lesions (arrow) in multiple vascular territories, which are typically associated with cerebral vasculitis. f | Wedge-shaped cortical infarcts (arrow) that are usually associated with the white matter lesions in cerebral vasculitis, shown with diffusion-weighted imaging (DWI). g | Bilateral middle cerebral artery segmental stenosis (arrows) depicted in a magnetic resonance angiogram (MRA).
Geraldes, R. et al. (2018) The current role of MRI in differentiating multiple sclerosis from its imaging mimics
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