1. Your synergistic outsourcing solution Powered by CTB Solutions, Inc Patent Pending

2. Tony Carita - CEO Marius Manole – CTO David Fenske – VP Business Delivery Andrea Bradbury –Quality Support Programming Support – Arobs 2

3. SynSource will facilitate successful management of: Provider identification Standardized RFI & RFP development Centralized proposal submission with access to historical data Automated comparative bid analysis Facilitated negotiation Contract development Performance monitoring Invoicing support tied to performance Scope change management Forecasting including real time updates based on actual study enrollment Flexible to meet individual study needs

4. Service Type RFIRFPNegotiationContractForecasting Earned Value InvoicingChangesCloseout 4

5. 5 Creating synergy across your organization

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7. 7 Financial Forecasts Instant access to top line forecast and projected spend Easily group or sort

8. Performance Data Establish variance thresholds and instantly access contracts that have variances Instant access to Gantt charts 8

9. ActivityStandard PracticeCostSynSourceSavings RFP Development Home grown Excel file (bid grid) Separate Word doc for RFP/SOW Managing multiple revisions No historical or industry data Manual process to ensure consistency Internal system maintenance $15-25K per RFP Integrated system for development of completed RFP (Bid Grid/SOW/RFP) Auto-generated text Collaborative document management 75-80% Negotiation/ Contract Finalization Manual process to compare Limited manual access to historical data Manual excel tracker to track offers Manual look up of prior bids $15-25K per contract Auto analysis of bids Facilitated negotiation process Tracks offers Access to historical data Central repository for negotiation records 50-60% Earned Value Project plan manually entered in Excel and/or MS Project Actual work performed manually entered and tracked each month Data manually transmitted to teams 8-12 hrs per project month Integration allows negotiated contract data to automatically populate project plan/GANTT Chart Plan vs. actual, remaining units and invoice detail automatically calculated based on units completed Complete transparency to teams and between sponsor and provider 80-90%

10. ActivityStandard PracticeCostSynSourceSavings Budget Forecasting Manually track work performed against plan and calculate remaining work. Manually forecast remaining work 8-12 hrs per project month Integration automates forecast based on earned value calculations & remaining work Can tie forecasted to actual vs planned recruitment rates for dynamic forecasting 80-90% Management of Invoices Manually review and approve invoice detail Manually resolve invoicing errors (10%) 1-2 hrs per project month Integration allows invoice detail to be autogenerated as an output of earned value Automated process utilizing contract data eliminates errors 80-90% Change in Scope Management Manually tracked in Excel1-2 hrs project month Change in scopes automatically tracked and incorporated into overall budget forecast 80-90% Internal ReportingManual process of rolling up study budgets, study forecasts and invoicing details. 10-15 hrs month All of the study budget, forecast, performance and invoicing details can be immediately accessed and filtered to view many different data scenarios. 80-90%

11. ActivityCostSavings Range$ Savings Range RFP Development$15-25k per RFP75%80% $11,250.00 $20,000.00 Negotiation/Contract Finalization$15-25k per RFP50%60% $7,500.00 $15,000.00 Earned Value8-12 hrs per project month80%90% $128.00 $216.00 Budget Forecasting8-12 hrs per project month80%90% $128.00 $216.00 Invoicing 1-2 hrs hrs per project month 80%90% $16.00 $36.00 Change in Scope Management 1-2 hrs hrs per project month 80%90% $120.00 $270.00 Internal Reporting10-15 hrs per month80%90% $1,200.00 $2,700.00 MonthlyYearly/Study20 Studies & RFPYear 2Year 3Total 3 Years $452 $24,174 $483,480 $580,176 $696,211 $1,759,867 $873 $45,476 $909,520 $1,091,424 $1,309,709 $3,310,653 Notes: 150Hourly Rate20No of on-going Projects 20%Annual Growth20No of RFPs

12. Our cloud hosting provides : Rapid Scaling and Application Uptime: Easy to add/remove application servers to an existing pool of load balanced web servers to handle all incoming requests Prevent Application Downtime: using f5 load balancing internet traffic is spread across multiple web servers. In the event a server becomes unavailable, the load balancer will redirect all traffic to the remaining online servers 12

13. Automated daily database backup Database information is automatically backed-up daily. The backup is copied into the cloud storage onto multi-redundant RAID 6 hard-drives and onto a second independent cloud provider Application backup image Application server image is kept into the cloud storage for rapidly creating application servers. Time to deploy a new application server – less than 30 minutes 13

14. 14 Presentation level ASP.Net 4.0 & Javascript - Base structure Silverlight 4 – Forms generator DevExpress XtraReports – Reporting Business Logic & Data Access Layers ADO.NET Entity Framework Database Microsoft SQL Server 2008

15. Logical separation of individual sponsor databases Unique access/Domain login Permission based access by email and password 15

16. An innovative product that will help your organization operate more effectively and efficiently Standardized templates that can easily be customized Work flow optimization Integrated bidding process to facilitate RFI/RFP development Reduced time from RFP to contract signature Tools that will improve performance measurement and invoicing accuracy tied to performance Access to historical data Automated budget forecasting tied to real time enrollment data Scope change management Flexibility to be easily user-customized during each step of the process. 16

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18. 18 Easily manage : Company profile Document templates & library Unit templates & library RFI/RFP/Review templates Internal users & permissions External providers Flexible to meet individual study needs

19. 19 Easily manage : Company profile Document templates & library Unit templates & library RFI/RFP/Review templates Internal users & permissions External providers Flexible to meet individual study needs

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21. 21 Easily manage : Company profile Document templates & library Unit templates & library RFI/RFP/Review templates Internal users & permissions External providers Flexible to meet individual study needs

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23. System templates can be: Routed to teams for online group review Simultaneous review Automatic version control

24. 24 Easily manage : Company profile Document templates & library Unit templates & library RFI/RFP/Review templates Internal users & permissions External providers Flexible to meet individual study needs

25. 25 Easily manage user roles and permissions

27. Create and send RFIs to multiple providers in minutes Receive automatic notifications System automatically tracks responses

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30. RFP development is automated and includes: Basic study information Detailed budget grid by unit of work to be performed System-generated detailed statement of work Flexible to meet individual study needs

31. Create and send and RFP to multiple providers in minutes Automated RFP review by sponsor team Summary table details proposals against benchmark Automated comparison/score of proposals System-facilitated negotiation Offers and counter-offers tracked

32. 32 Easily send proposals to study teams for evaluation Quickly schedule bid defense meetings Select bidder

33. 33 Instantly view –High and low bids –Sponsor and provider offers Easily make new offer

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35. One click automated earned value reports including cost variance and balance of work

36. Payments can be based on - Milestones - Units completed - Mixed model Pending invoices are auto-generated as providers complete study performance 36

37. One click study forecasts with user defined: Number of periods Forecasting period (monthly, quarterly or yearly) Forecasting can be tied to real time enrollment data to dynamically reforecast budget and timeline based on actual vs planned enrollment.

38. 38 One click access to develop a change in scope

39. Powered by CTB Solutions, Inc Patent Pending