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Update on the Diagnosis and Management of CTEPH in Latin America

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Presentation on theme: "Update on the Diagnosis and Management of CTEPH in Latin America"— Presentation transcript:

1 Update on the Diagnosis and Management of CTEPH in Latin America

2 Clinical Classification of PH

3 Pulmonary Endarterectomy Surgery: Scar Tissue Removal

4 Results of PE

5 History of PE Is a Risk Factor for CTEPH

6 Diagnosis of CTEPH (SCAR): A Step-Wise Process

7 SCAR: S = Suspect

8 SCAR: C = Confirm

9 SCAR: AR = Assess Risk

10 CTEPH Is Not Just a Clot Problem

11 CTEPH Is Not Just a Clot Problem (cont)

12 CTEPH Treatment Algorithm

13 Key Principles Regarding the Management of CTEPH

14 Key Principles Regarding the Management of CTEPH (cont)

15 CTEPH Treatment: Patients Deemed Operable

16 CTEPH Treatment Algorithm (cont)[a]

17 Pulmonary Endarterectomy Specimen: Significant Thromboembolic Material

18 UCSD Experience With Pulmonary Endarterectomy

19 UCSD Experience With Pulmonary Endarterectomy (cont)

20 CTEPH: Determining Operability

21 Potentially Inoperable Patient With CTEPH

22 CTEPH Treatment Algorithm (cont)

23 Riociguat for the Treatment of Chronic Thromboembolic Pulmonary Hypertension (CHEST-1)

24 Riociguat: Mechanism of Action

25 CHEST-1*: Mean Change From Baseline in 6MWD

26 CHEST-2: Long-Term Extension Study of Riociguat for CTEPH

27 AEs in the CHEST-2 Study

28 Potential Scenarios for Targeted Medical Therapy in CTEPH

29 Patient Offered BPA

30 Pulmonary Endarterectomy and BPA: Comments

31 Summary and Conclusions

32 Abbreviations

33 Abbreviations (cont)


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