1. A Framework for Diagnosing and Treating CTEPH

3. Program Goals

4. Pulmonary Embolism and CTEPH

5. CTEPH Mortality

6. CTEPH Risk Factors

7. Autopsy Findings

8. Case Presentation

9. Case Presentation (cont)

10. Case Presentation (cont)

11. Case Presentation (cont)

12. Case Presentation (cont)

13. Echocardiographic Findings

14. The Patient’s Echocardiogram

15. Ventilation-Perfusion Scan

16. Differential Diagnosis of Major Vessel Pulmonary Vascular Disease

17. Differential Diagnosis (cont)

18. CT Angiography: CTEPH

19. CT Angiogram: CTEPH (cont)

20. CT Angiogram of the Pulmonary Arteries: CTEPH

21. CT Angiogram (cont)

22. Right Pulmonary Artery Angiogram

23. Left Pulmonary Artery Angiogram

24. Right-Heart Catheterization Data

25. Right-Heart Catheterization Data (cont)

26. Main Principles of Surgery for CTEPH

27. Main Principles of Surgery for CTEPH (cont)

28. Thromboendarterectomy Specimen

29. Factors That Affect Decisions About Operability

30. How Do We Treat Inoperable CTEPH or Persistent PH After Pulmonary Endarterectomy?

31. Treating Inoperable CTEPH or Persistent PH After Pulmonary Endarterectomy (cont)

32. Targets for Current Therapies in PAH

33. Bosentan in CTEPH (BENEFIT)

34. Riociguat for the Treatment of CTEPH (CHEST-1) Methods

36. Riociguat for CTEPH Secondary Endpoints

37. Riociguat for CTEPH Secondary Endpoints (cont)

38. Summary

39. Abbreviations

40. Abbreviations (cont)

41. References

42. References (cont)

43. References (cont)