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Effects of BRG1 depletion in the proliferation of lung cancer cells with amplification at the MYC family of genes and in MAX-deficient cells, after reconstitution.

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Presentation on theme: "Effects of BRG1 depletion in the proliferation of lung cancer cells with amplification at the MYC family of genes and in MAX-deficient cells, after reconstitution."— Presentation transcript:

1 Effects of BRG1 depletion in the proliferation of lung cancer cells with amplification at the MYC family of genes and in MAX-deficient cells, after reconstitution of MAX. A, MTT assay to determine viability, after depleting BRG1 and in the scramble (scr) co... Effects of BRG1 depletion in the proliferation of lung cancer cells with amplification at the MYC family of genes and in MAX-deficient cells, after reconstitution of MAX. A, MTT assay to determine viability, after depleting BRG1 and in the scramble (scr) control, of cells carrying amplification of MYC (H446, H460, and H82), MYCN (H69), or MYCL (HCC33 and H1963). Lines, the number of viable cells relative to the total number of cells at 0 hours. Error bars, SD. NS, not significant; *, P < 0.05; **, P < B, left, MTT assays of MAX-deficient cells carrying the indicated constructs. Right, images of the MTT assay of Lu134 cells. Octavio A. Romero et al. Cancer Discovery 2014;4: ©2014 by American Association for Cancer Research

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