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Circ Cardiovasc Interv

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Presentation on theme: "Circ Cardiovasc Interv"— Presentation transcript:

1 Circ Cardiovasc Interv
Pharmacoinvasive Strategy Versus Primary Percutaneous Coronary Intervention in Patients With ST-Segment–Elevation Myocardial Infarction by Doo Sun Sim, Myung Ho Jeong, Youngkeun Ahn, Young Jo Kim, Shung Chull Chae, Taek Jong Hong, In Whan Seong, Jei Keon Chae, Chong Jin Kim, Myeong Chan Cho, Seung-Woon Rha, Jang Ho Bae, Ki Bae Seung, and Seung Jung Park Circ Cardiovasc Interv Volume 9(9):e003508 August 31, 2016 Copyright © American Heart Association, Inc. All rights reserved.

2 The study flow diagram of patients.
The study flow diagram of patients. KAMIR indicates Korea Acute Myocardial Infarction Registry; NSTEMI, non-ST-segment–elevation myocardial infarction; PCI, percutaneous coronary intervention; PI, pharmacoinvasive; PPCI, primary percutaneous coronary intervention; and STEMI, ST-segment–elevation myocardial infarction. Doo Sun Sim et al. Circ Cardiovasc Interv. 2016;9:e003508 Copyright © American Heart Association, Inc. All rights reserved.

3 Adjusted cumulative major adverse cardiac events at 12 months between pharmacoinvasive (PI) and primary percutaneous coronary intervention (PPCI) groups after propensity score matching. Adjusted cumulative major adverse cardiac events at 12 months between pharmacoinvasive (PI) and primary percutaneous coronary intervention (PPCI) groups after propensity score matching. Doo Sun Sim et al. Circ Cardiovasc Interv. 2016;9:e003508 Copyright © American Heart Association, Inc. All rights reserved.

4 Hazard ratios (HR) for 12-month major adverse cardiac events in propensity-matched cohort according to subgroup. Hazard ratios (HR) for 12-month major adverse cardiac events in propensity-matched cohort according to subgroup. CI indicates confidence interval; EMS, emergency medical system; GRACE, Global Registry of Acute Coronary Events; HR, hazard ratio; PI, pharmacoinvasive; and PPCI, primary percutaneous coronary intervention. Doo Sun Sim et al. Circ Cardiovasc Interv. 2016;9:e003508 Copyright © American Heart Association, Inc. All rights reserved.

5 Relationship between percutaneous coronary intervention (PCI)-related delay and 12-month major adverse cardiac events (MACE) as a linear regression model. Relationship between percutaneous coronary intervention (PCI)-related delay and 12-month major adverse cardiac events (MACE) as a linear regression model. The y axis displays the log hazard ratio of 12-month MACE with pharmacoinvasive relative to primary percutaneous coronary intervention (PPCI), whereas the x axis is PCI-related delay in minutes. Dotted lines represent 95% confidence intervals. Equipoise between pharmacoinvasive and PPCI occurred at ≈100 min (vertical dashed line). HR indicates hazard ratio; PCI, percutaneous coronary intervention; PI, pharmacoinvasive; and PPCI, primary percutaneous coronary intervention. Doo Sun Sim et al. Circ Cardiovasc Interv. 2016;9:e003508 Copyright © American Heart Association, Inc. All rights reserved.


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