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Cushing's disease  Xavier Bertagna, MD, PhD, Laurence Guignat, MD, Lionel Groussin, MD, PhD, Jérôme Bertherat, MD, PhD  Best Practice & Research Clinical.

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Presentation on theme: "Cushing's disease  Xavier Bertagna, MD, PhD, Laurence Guignat, MD, Lionel Groussin, MD, PhD, Jérôme Bertherat, MD, PhD  Best Practice & Research Clinical."— Presentation transcript:

1 Cushing's disease  Xavier Bertagna, MD, PhD, Laurence Guignat, MD, Lionel Groussin, MD, PhD, Jérôme Bertherat, MD, PhD  Best Practice & Research Clinical Endocrinology & Metabolism  Volume 23, Issue 5, Pages (October 2009) DOI: /j.beem Copyright © 2009 Elsevier Ltd Terms and Conditions

2 Fig. 1 (A & B) Typical aspect of a patient with Cushing's syndrome: centripetal fat depositing with truncal obesity contrasting with the muscular atrophy of the thighs and legs (Personal collection). Best Practice & Research Clinical Endocrinology & Metabolism  , DOI: ( /j.beem ) Copyright © 2009 Elsevier Ltd Terms and Conditions

3 Fig. 2 Pituitary corticotroph adenoma revealed by MRI in Cushing's disease. A typical hypointense signal is observed with T1-weighted images after gadolinium injection (Personal collection). Best Practice & Research Clinical Endocrinology & Metabolism  , DOI: ( /j.beem ) Copyright © 2009 Elsevier Ltd Terms and Conditions

4 Fig. 3 Diagnostic flow-chart in a patient with clinical suspicion of Cushing's syndrome. Best Practice & Research Clinical Endocrinology & Metabolism  , DOI: ( /j.beem ) Copyright © 2009 Elsevier Ltd Terms and Conditions


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