1. From: In Vivo Study of Changes in Refractive Index Distribution in the Human Crystalline Lens with Age and Accommodation
Invest. Ophthalmol. Vis. Sci ;49(6): doi: /iovs
Figure Legend:
Schematic representation of the analysis procedure. (A–D) MSE images obtained at TEs of 12, 24, 36, and 48 ms, respectively. Note the progressive decrease in intensity of lens pixels with increasing echo time. (E) Custom software was used to identify the lens pixels (shown in saturated white for the MSE image at 12 ms) with minimal user input. (F) Intensity of a central lens pixel, plotted against echo time. The data were fitted with a mono-exponential decay function to obtain R 2 and calculate the refractive index for each pixel. (G) A composite refractive index map of all pixels contained within the lens. Note the brighter areas of higher refractive index at the center and darker areas of lower refractive index at the periphery. Noise in the refractive index data necessitated use of spatial averaging procedures.
Date of download: 10/9/2017
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