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Clinical and genetic analyses of familial and sporadic frontotemporal dementia patients in Southern Italy  Rosa Capozzo, Celeste Sassi, Monia B. Hammer,

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Presentation on theme: "Clinical and genetic analyses of familial and sporadic frontotemporal dementia patients in Southern Italy  Rosa Capozzo, Celeste Sassi, Monia B. Hammer,"— Presentation transcript:

1 Clinical and genetic analyses of familial and sporadic frontotemporal dementia patients in Southern Italy  Rosa Capozzo, Celeste Sassi, Monia B. Hammer, Simona Arcuti, Chiara Zecca, Maria R. Barulli, Rosanna Tortelli, J. Raphael Gibbs, Cynthia Crews, Davide Seripa, Francesco Carnicella, Claudia Dell'Aquila, Marco Rossi, Filippo Tamma, Francesco Valluzzi, Bruno Brancasi, Francesco Panza, Andrew B. Singleton, Giancarlo Logroscino  Alzheimer's & Dementia: The Journal of the Alzheimer's Association  Volume 13, Issue 8, Pages (August 2017) DOI: /j.jalz Copyright © Terms and Conditions

2 Fig. 1 Pedigrees of frontotemporal dementia (FTD) families (A–H).
Alzheimer's & Dementia: The Journal of the Alzheimer's Association  , DOI: ( /j.jalz ) Copyright © Terms and Conditions

3 Fig. 1 Pedigrees of frontotemporal dementia (FTD) families (A–H).
Alzheimer's & Dementia: The Journal of the Alzheimer's Association  , DOI: ( /j.jalz ) Copyright © Terms and Conditions

4 Fig. 1 Pedigrees of frontotemporal dementia (FTD) families (A–H).
Alzheimer's & Dementia: The Journal of the Alzheimer's Association  , DOI: ( /j.jalz ) Copyright © Terms and Conditions

5 Fig. 1 Pedigrees of frontotemporal dementia (FTD) families (A–H).
Alzheimer's & Dementia: The Journal of the Alzheimer's Association  , DOI: ( /j.jalz ) Copyright © Terms and Conditions

6 Fig. 2 Clinical frontotemporal dementia (FTD) subtypes (familial: behavioral variant of frontotemporal dementia [bvFTD] 50%, primary progressive aphasia [PPA] 18%, semantic dementia [SD] 0%, FTD-memory onset 32%; sporadic: bvFTD 69%, PPA 31%, SD 0%). Alzheimer's & Dementia: The Journal of the Alzheimer's Association  , DOI: ( /j.jalz ) Copyright © Terms and Conditions

7 Fig. 3 Behavior and language changes observed at onset in the whole cohort of familial and sporadic frontotemporal dementia cases without considering diagnostic subtypes. Abbreviations: FTD, frontotemporal dementia; PPA, primary progressive aphasia. Alzheimer's & Dementia: The Journal of the Alzheimer's Association  , DOI: ( /j.jalz ) Copyright © Terms and Conditions

8 Fig. 4 Frequencies of behavior and language changes at onset, respectively, in behavioral variant of frontotemporal dementia (bvFTD) and primary progressive aphasia (PPA) both in familial and sporadic forms. Alzheimer's & Dementia: The Journal of the Alzheimer's Association  , DOI: ( /j.jalz ) Copyright © Terms and Conditions

9 Fig. 5 Number of symptoms (1–3; 4–6; 7–9) referred at onset in familial and sporadic frontotemporal dementia patients. Abbreviations: bvFTD, behavioral variant of frontotemporal dementia; PPA, primary progressive aphasia. Alzheimer's & Dementia: The Journal of the Alzheimer's Association  , DOI: ( /j.jalz ) Copyright © Terms and Conditions


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