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Multiple Myeloma Presenting as Mandibular Ill-Defined Radiolucent Lesion With Numb Chin Syndrome: A Case Report Husam G. Elias, MD, DMD, Jacob Scott, MD, Leland Metheny, MD, Faisal A. Quereshy, MD, DDS Journal of Oral and Maxillofacial Surgery Volume 67, Issue 9, Pages (September 2009) DOI: /j.joms Copyright © 2009 American Association of Oral and Maxillofacial Surgeons Terms and Conditions
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Figure 1 Neck CT scan showing left-sided osteolytic lesion.
Elias et al. Multiple Myeloma With Radiolucent Lesion. J Oral Maxillofac Surg 2009. Journal of Oral and Maxillofacial Surgery , DOI: ( /j.joms ) Copyright © 2009 American Association of Oral and Maxillofacial Surgeons Terms and Conditions
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Figure 2 Panoramic radiograph showing an ill-defined unilocular radiolucency extending anteriorly to the premolar region, scalloped around premolar roots without resorption; it also spares the lower border of the mandible. Elias et al. Multiple Myeloma With Radiolucent Lesion. J Oral Maxillofac Surg 2009. Journal of Oral and Maxillofacial Surgery , DOI: ( /j.joms ) Copyright © 2009 American Association of Oral and Maxillofacial Surgeons Terms and Conditions
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Figure 3 Cone beam CT scan of mandibular lesion, showing 3-dimensional reconstruction of the lesion as well as extension into the anteroposterior axial, sagittal, and coronal sections. Elias et al. Multiple Myeloma With Radiolucent Lesion. J Oral Maxillofac Surg 2009. Journal of Oral and Maxillofacial Surgery , DOI: ( /j.joms ) Copyright © 2009 American Association of Oral and Maxillofacial Surgeons Terms and Conditions
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Figure 4 Incisional biopsy specimen of mandibular lesion.
Elias et al. Multiple Myeloma With Radiolucent Lesion. J Oral Maxillofac Surg 2009. Journal of Oral and Maxillofacial Surgery , DOI: ( /j.joms ) Copyright © 2009 American Association of Oral and Maxillofacial Surgeons Terms and Conditions
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Figure 5 The photomicrographs show sheets of rather uniform medium-sized round/oval cells with eccentric nuclei, inconspicuous nucleoli, and abundant eosinophilic cytoplasm with a peri-nuclear halo. A rare binucleated cell is noted. No organoid arrangement is seen. (H&E stain.) Elias et al. Multiple Myeloma With Radiolucent Lesion. J Oral Maxillofac Surg 2009. Journal of Oral and Maxillofacial Surgery , DOI: ( /j.joms ) Copyright © 2009 American Association of Oral and Maxillofacial Surgeons Terms and Conditions
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Figure 6 Osteolytic lesions of humerus and femoral neck.
Elias et al. Multiple Myeloma With Radiolucent Lesion. J Oral Maxillofac Surg 2009. Journal of Oral and Maxillofacial Surgery , DOI: ( /j.joms ) Copyright © 2009 American Association of Oral and Maxillofacial Surgeons Terms and Conditions
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