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Role of p38 MAPK Pathway in Induction of iNOS Expression in Neutrophils and Peripheral Blood Mononuclear Cells in Patients With Squamous Cell Carcinoma.

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Presentation on theme: "Role of p38 MAPK Pathway in Induction of iNOS Expression in Neutrophils and Peripheral Blood Mononuclear Cells in Patients With Squamous Cell Carcinoma."— Presentation transcript:

1 Role of p38 MAPK Pathway in Induction of iNOS Expression in Neutrophils and Peripheral Blood Mononuclear Cells in Patients With Squamous Cell Carcinoma of the Oral Cavity  Wioletta Ratajczak-Wrona, PhD, Ewa Jablonska, DSc, Magdalena Marcinczyk, PhD, Zyta Grabowska, DDS, DSc, Leszek Piotrowski, DDS  Journal of Oral and Maxillofacial Surgery  Volume 67, Issue 11, Pages (November 2009) DOI: /j.joms Copyright © 2009 American Association of Oral and Maxillofacial Surgeons Terms and Conditions

2 Figure 1 MAPK signaling pathways.
Ratajczak-Wrona et al. Role of p38 MAPK Pathway in Induction of iNOS Expression. J Oral Maxillofac Surg 2009. Journal of Oral and Maxillofacial Surgery  , DOI: ( /j.joms ) Copyright © 2009 American Association of Oral and Maxillofacial Surgeons Terms and Conditions

3 Figure 2 Western blot analysis of iNOS protein expression in PMNs and PBMCs. A, unstimulated PMNs, B, PMNs+rhIL-15, C, PMNs+rhIL-18, D, unstimulated PBMCs, E, PBMCs+rhIL-15, F, PBMCs+rhIL-18. Ratajczak-Wrona et al. Role of p38 MAPK Pathway in Induction of iNOS Expression. J Oral Maxillofac Surg 2009. Journal of Oral and Maxillofacial Surgery  , DOI: ( /j.joms ) Copyright © 2009 American Association of Oral and Maxillofacial Surgeons Terms and Conditions

4 Figure 3 Western blot analysis of phospho-p38 MAPK protein expression in PMNs and PBMCs. A, unstimulated PMNs, B, PMNs+rhIL-15, C, PMNs+rhIL-18, D, unstimulated PBMCs, E, PBMCs+rhIL-15, F, PBMCs+rhIL-18. Ratajczak-Wrona et al. Role of p38 MAPK Pathway in Induction of iNOS Expression. J Oral Maxillofac Surg 2009. Journal of Oral and Maxillofacial Surgery  , DOI: ( /j.joms ) Copyright © 2009 American Association of Oral and Maxillofacial Surgeons Terms and Conditions

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