1. Relationship of Circulating CXCR4 + EPC with Prognosis of Mild Traumatic Brain Injury Patients
Yunpeng Lin 1, # ;Lan Lan Luo 2, # ;Jian Sun 1 ;Weiwei Gao 1 ;Ye Tian 1 ;Eugene Park 3 ;Andrew Baker 3 ;Jieli Chen 4, 5 ;Rongcai Jiang 1 ;Jianning Zhang 1 ;
1 Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin Neurological Institute, Key Laboratory of Post-neurotrauma Neuro-repair and Regeneration in Central Nervous System, Ministry of Education and Tianjin City, Tianjin , China ; 2 Department off Psychological Science, Tianjin Medical University General Hospital, Tianjin , China ; 3 Department of Traumatic Critical Care Unit, St. Michael#cod#x02019;s Hospital, Toronto, Canada ; 4 Department of Neurology, Henry Ford Hospital, Detroit, MI USA ; 5 Department of Geriatrics, Tianjin Geriatrics Institute, Tianjin Medical University General Hospital, Tianjin, China ;
Figure Number of CD34 + , CD and EPCs in the peripheral blood. A Number of circulating EPCs in mild and moderate traumatic brain injury TBI patients, showing a similar tendency of #cod#x0201C;from low to high#cod#x0201D;, peaked at 7 days and then gradually decreased and was significantly higher than that in the control group at 7 and 14 days after TBI #cod#x0002A; p #cod#x0003C; B Mild TBI patients were further divided into a good prognosis group group A and a poor prognosis group group B. There was no significant difference in EPC number among group A, group B and moderate TBI group P #cod#x0003E; C CD34 + cell number in the peripheral blood of mild and moderate TBI patients was very high in the early stage after TBI and began to significantly decrease at 7 days after TBI, and was significantly higher than control group at 1, 4, 7 and 14 days after TBI #cod#x0002A; p #cod#x0003C; There was no significant difference in CD34 + cell number between mild and moderate TBI groups p #cod#x0003E; D CD cell number in the peripheral blood of all TBI patients was also very high in the early stage after TBI and began to significantly decrease at 7 days after TBI, and was significantly higher than the control group at 1, 4, 7, 14 and 21 days after TBI #cod#x0002A; p #cod#x0003C; There was no significant difference in CD cell number between mild and moderate TBI group p #cod#x0003E; 0.05.
Aging and Disease,null,8(1), Doi: /AD