1. Ischemia-induced Angiogenesis is Attenuated in Aged Rats
Tang Yaohui 1, 2 ;Wang Liuqing 3 ;Wang Jixian 5 ;Lin Xiaojie 1 ;Wang Yongting 1 ;Jin Kunlin 3, 4 ;Yang Guo-Yuan 1, 5 ;
1 Neuroscience and Neuroengineering Center, Med-X Research Institute, Shanghai Jiao Tong University, Shanghai , China ; 2 Department of Orthopaedic surgery, School of medicine, Stanford University, CA 94305, USA ; 3 Department of Neurology, the First Affiliated Hospital, Wenzhou Medical University, Zhejiang, , China ; 4 Department of Pharmacology and Neuroscience, University of North Texas Health Science Center at Fort Worth, TX 76203, USA ; 5 Shanghai Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University Shanghai , China ;
Figure 3. The number of blood vessels in young adult and aged rat brain after focal ischemia. Photomicrographs showed lectin and Glut-1 staining in the ipsilateral hemisphere in young adult ischemic A and B, left panel and aged ischemic brain right panel. Scale bar =20 #cod#x000B5;m. Bar graph showed that the quantitative number of blood vessels in ipsilateral hemisphere of young adult and aged rat brain from lectin C and Glut-1 D staining. Data were presented as mean#cod#x000B1;SD. #cod#x0002A;, p #cod#x0003C;0.05, the number of microvessels of ipsilateral hemisphere in young adult ischemic vs. that in aged ischemic rats. N=6 per group.
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