1. Date of download: 7/7/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Increased Antiangiogenic Protein Expression in the Skeletal Muscle of Diabetic Swine and Patients Arch Surg. 2008;143(5):463-470. doi:10.1001/archsurg.143.5.463 Mean porcine skeletal muscle levels of angiostatin were increased 1.70-fold in swine with diabetes mellitus (DM) relative to nondiabetic (ND) swine (A), and mean porcine skeletal muscle levels of endostatin were increased 1.84-fold in swine with DM relative to ND swine (B). DU indicates densitometry units; error bars, standard error of the mean. *P <.05. Figure Legend:

2. Date of download: 7/7/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Increased Antiangiogenic Protein Expression in the Skeletal Muscle of Diabetic Swine and Patients Arch Surg. 2008;143(5):463-470. doi:10.1001/archsurg.143.5.463 Mean human skeletal muscle levels of angiostatin demonstrated no significant differences between patients with diabetes mellitus (DM) and nondiabetic (ND) patients (A), and mean human skeletal muscle levels of endostatin were increased 1.69-fold in patients with DM relative to ND patients (B). DU indicates densitometry units; error bars, standard error of the mean. *P <.05. Figure Legend:

3. Date of download: 7/7/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Increased Antiangiogenic Protein Expression in the Skeletal Muscle of Diabetic Swine and Patients Arch Surg. 2008;143(5):463-470. doi:10.1001/archsurg.143.5.463 Mean porcine skeletal muscle levels of active matrix metalloproteinase 2 (MMP-2) were significantly increased in swine with diabetes mellitus (DM) relative to nondiabetic (ND) swine (A), and active matrix metalloproteinase 9 (MMP-9) expression demonstrated no significant differences between swine with DM and ND swine (B). DU indicates densitometry units; error bars, standard error of the mean. *P <.05. Figure Legend:

4. Date of download: 7/7/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Increased Antiangiogenic Protein Expression in the Skeletal Muscle of Diabetic Swine and Patients Arch Surg. 2008;143(5):463-470. doi:10.1001/archsurg.143.5.463 Mean human skeletal muscle levels of matrix metalloproteinase 2 (MMP-2) activity were significantly increased in patients with diabetes mellitus (DM) relative to nondiabetic (ND) patients (A), and matrix metalloproteinase 9 (MMP-9) activity demonstrated no significant differences between patients with DM and ND patients (B). DU indicates densitometry units; error bars, standard error of the mean. *P <.05. Figure Legend: