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Lung Cancer
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Histologic Classification of Non-small Cell Lung Cancer
Squamous cell (epidermoid) carcinoma spindle cell variant Adenocarcinoma acinar papillary bronchoalveolar solid tumor with mucin Large cell carcinoma giant cell clear cell Adenosquamous carcinoma Undifferentiated carcinoma
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TNM Staging Stage TNM 5-year Survival O Carcinoma in situ 1A TIN0M0
67% 1B T2N0M0 57% IIA T1N1M0 55% IIB T2N1M0 T3N0M0 38% IIIA T3N1M0 T1N2M0 T2-3N2M0 23% IIIB T4N0-2 T1-4N3M0 5% IV T1-4N0-3M1 1% Survival is very heavily dependent upon TNM tumor stage Stages 1A through IIIB are dependent on the T and N classification Stage IV disease is defined by metastatic disease Major distinctions: Stage IIA and stage IIB Stage IIIA and stage IIIB
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--Regional nodal stations for lung cancer staging
Ko, J. P. et al. Am. J. Roentgenol. 2000;174: Copyright © 2006 by the American Roentgen Ray Society
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--Regional nodal stations for lung cancer staging
Ko, J. P. et al. Am. J. Roentgenol. 2000;174: Copyright © 2006 by the American Roentgen Ray Society
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--Regional nodal stations for lung cancer staging
Ko, J. P. et al. Am. J. Roentgenol. 2000;174: Copyright © 2006 by the American Roentgen Ray Society
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--Regional nodal stations for lung cancer staging
Ko, J. P. et al. Am. J. Roentgenol. 2000;174: Copyright © 2006 by the American Roentgen Ray Society
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STAGE 0 TisN0M0 TREATMENT ENDOSCOPY SURGERY RADIATION
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STAGE 1A T1N0M0 TREAMENT SURGERY RADIATION
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STAGE 1B T2N0M0 TREATMENT SURGERY RADIATION
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STAGE IIA T1N1M0 TREATMENT SURGERY RADIATION CHEMOTHERAPY
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STAGE IIB T2N1M0 T3N0M0 TREATMENT SURGERY RADIATION CHEMOTHERAPY
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STAGE IIIA T3N1M0 T1N2M0 T2-3N2M0 TREATMENT RADIATION CHEMOTHERAPY
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STAGE IIIB T4N0-2M0 T1-4N3M0 TREATMENT RADIATION CHEMOTHERAPY
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STAGE IV T1-4 N0-3M1 TREAMENT RADIATION CHEMOTHERAPY SURGERY
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SPECIAL SITUATIONS Pancoast’s Tumor Medically Unfit
Radiation Chemotherapy Surgery Medically Unfit Ablation Bronchial Obstruction Stent Laser Puotodynamic Therapy
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SUMMARY Difficult disease to treat usually presents at late stage
Best results when found early Screening though effective
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