1. 1. Complete Most Missed Quiz: DNA – then complete the bellwork. 2. Copy the paragraph and fill in the blanks using these words: G1 G2 interphase mitosis replicate synthesis MITOSIS is the process of cell division or growing more cells. Before a cell can divide, it must REPLICATE its DNA. Prior to replicating the DNA, the chromosomes grow and prepare themselves for DNA replication in the G1 phase. The chromosomes replicate themselves in the S or SYNTHESIS phase of the cell cycle. After the S phase, the cell goes through the G2 phase where it prepares itself for mitosis. The G1, S, and G2 stages are collectively called INTERPHASE.

2. Collect Today Page 56 – Interphase Handout Assigned Buff Binder Quiz #1 Makeup – (Today) T/T Quiz Makeup – (Wednesday) Cell Cycle/Vocabulary Quiz – (Thursday) Page 58 – Cell Cycle Foldable (Thursday) Late Page 53 - Codon Face Project (-50%)

3. Unit 4 – Cell Cycle Definitions Due Friday (11/6/15) All Parts Due Friday (11/13/15) 1.Allele 2.Anaphase 3.Cancer 4.Cell Cycle 5.Centriole 6.Centromere 7.Chromatid 8.Chromosome 9.Crossing Over 10.Cytokinesis 11.Daughter Cell 12.Diploid 13.Electrophoresis 14.Frameshift Mutation 15.Gamete 16.Gene 17.Genetic Disorder 18.Genome 19.Haploid 20.Interphase 21.Karyotype 22.Meiosis 23.Metaphase 24.Mitosis 25.Mutation 26.Offspring 27.Point Mutation 28.Prophase 29.Sexual Reproduction 30.Somatic 31.Telophase 32.Tumor Pg 54

4. Essential Question What are the four stages of mitosis? Standard B.5A – Describe the stages of the Cell Cycle, including Deoxyribonucleic acid (DNA) replication and mitosis, and the importance of the cell cycle to the growth of an organism. Pg 57

5. Cell Cycle Re-cap 1.G 1 2.S phase 3.G 2 4.M phase Remember that G 1, S, and G 2 together are known as interphase and a cell spends most of it’s life in interphase.

6. Reasons for cell division 1.To prevent them from being inefficient in getting nutrients surface area to volume ratio 2.To reproduce For example: bacteria can reproduce asexually 3.To repair damaged tissue For example: if you get a paper cut 4.To grow an organism

7. Mitosis in the Cell

8. There are many words that describe DNA in it’s various forms… A. DNA is usually found as chromatin while the cell is doing its normal job. 1. Chromatin is the granular material visible within the nucleus that consists of DNA tightly coiled around proteins.

9. B. Before a cell divides, chromatin (DNA) coils up to form chromosomes. 1.Chromosomes are made up of DNA and proteins.

11. 2. All organisms do not have the same number of chromosomes. 3. Human cells have 46 chromosomes. 4. Chromosomes are only visible during cell division.

12. C. Before each cell division, each chromosome is replicated, or copied. D. For this reason, each chromosome consists of two identical sister chromatids. DRAW AND LABEL

13. E. Each pair of sister chromatids is attached at an area called the centromere. A human body cell entering cell division contains 46 chromosomes or 92 chromatids. DRAW AND LABEL

14. Now let’s talk about mitosis… II. The two main stages of cell division are mitosis and cytokinesis.

15. Cyto = Cell Kinesis = Movement

16. A. The first stage, division of the cell nucleus, is called mitosis. B. The second stage, division of the cytoplasm, is called cytokinesis.

17. C. Reproduction by mitosis is classified as asexual. 1. Unicellular organisms reproduce in this manner. 2. Mitosis is also the source of new cells when a multicellular organism grows and develops.

18. D. As you remember, a cell spends most of its time in Interphase. During interphase, a cell does its normal job, grows larger, copies its DNA, and prepares for cell division. DRAW THIS!

19. III. Mitosis A. Biologists divide the events of mitosis into 4 phases: prophase, metaphase, anaphase, and telophase (PMAT).

20. During prophase, the chromosomes become visible, the centrioles separate to opposite sides of the cell, the chromosomes attach to the spindle, the nucleolus disappears, and the nuclear envelope breaks down. DRAW THIS!

21. B. The centrioles are two tiny structures located in the cytoplasm near the nuclear envelope that help organize the spindle. C. The spindle fibers are a fanlike microtubule structure that helps separate the chromosomes.

22. During metaphase, the chromosomes line up across the center of the cell (Middle). During anaphase, the centromeres that join the sister chromatids split and the chromosomes move until they have separated into two groups near the poles of the spindle (Away). DRAW THIS!

24. During telophase, the chromosomes begin to disperse into a tangle of dense material, the nuclear envelope reforms around each cluster of chromosomes, the spindle breaks apart, and the nucleolus becomes visible in each nucleus. DRAW THIS!

25. ProphaseMetaphase AnaphaseTelophase PMAT Always remember…

26. D. Cell division is not complete after telophase. Cytokinesis is division of the cytoplasm.

28. Cell Cycle Foldable Create a foldable explaining the different phases of the cell cycle. Concrete Spellings Be creative in the representation of the phases. Must include a minimum of 5 colors Will be due in the tray on Thursday Small Group CHAMPS PG 58

29. In animal cells, cytokinesis occurs when the cell membrane is drawn inward until the cytoplasm is pinched into two equal parts. In plant cells, cytokinesis occurs when a cell plate forms cleavage furrow between the divided nuclei gradually developing into a separating membrane.

30. Mitosis in the Cell

34. Let’s practice… On the back of your page, number 1-5. On the next slide, you will see 5 pictures. You need to figure out what phase each one is in and write it down.

35. 1 2 34 5

36. Collect Today Page 56 – Interphase Handout Assigned Buff Binder Quiz #1 Makeup – (Today) T/T Quiz Makeup – (Wednesday) Cell Cycle/Vocabulary Quiz – (Thursday) Page 58 – Cell Cycle Foldable (Thursday) Late Page 53 - Codon Face Project (-50%)