1. Blood and Lymph Vessels VIBS 443/602

2. OBJECTIVES 1.LAYERS IN VASCULAR WALLS 2.CLASSIFICATION OF VESSELS 3.VARIATION IN MICROVASCULATURE 4.LYMPHATIC SYSTEM

3. Introduction Multicellular Organisms Need 3 Mechanisms --------------------------------------------------------------- 1.Distribute oxygen, nutrients, and hormones 2.Collect waste 3.Transport waste to excretory organs CARDIOVASCULAR SYSTEM

4. HEART PRODUCES BLOOD PRESSURE (SYSTOLE) Vessels are structurally adapted to physical requirements and metabolic needs

5. CARDIOVASCULAR SYSTEM ELASTIC ARTERIES- CONDUCT BLOOD AND MAINTAIN PRESSURE DURING DIASTOLE

6. CARDIOVASCULAR SYSTEM MUSCULAR ARTERIES - DISTRIBUTE BLOOD, MAINTAIN PRESSURE ARTERIOLES - PERIPHERAL RESISTANCE AND DISTRIBUTE BLOOD CAPILLARIES - EXCHANGE NUTRIENTS AND WASTE VENULES - COLLECT BLOOD FROM CAPILLARIES (EDEMA)

8. LAYERS IN VASCULAR WALL LAYERCOMPOSITION TUNICA INTIMAENDOTHELIUM (SUBENDOTHELIA CT. INTERNAL ELASTIC LAMINA) TUNICA MEDIASMOOTH MUSCLE (ELASTIC LAMELLAE, EXTERNAL ELASTIC LAMINA) TUNICACONNECTIVE TISSUE ADVENTITIA (LONGITUDINAL SMOOTH MUSCLE, VASA VASORUM)

9. 17

11. Slide 427 aorta427

12. Slide 427427

13. 432432 lung

14. 432

15. 472472 fallopian tube

16. 426426 renal

17. EM 9 of arteriole: 1.Endothelial cell 2.Internal elastic membrane 3.Smooth muscle cell

18. VENULE MUSCULAR ARTERY Note difference in density of smooth muscle cells.

19. EM 17 of capillary in the lamina propria of the intestine 1.Smooth muscle cell 2.Capillary 3.Endothelial cell

20. EM 10a: pericyte in vessel wall; 20,000x 1.Lumen 2.Endothelial cell 3.Tight junction

21. liver kidney/adrenal muscle/brain basal lamina

22. liver kidney/adrenal muscle/brain basal lamina

23. CONTINUOUS FENESTRATED SINUSOIDAL

24. TYPES OF CAPILLARIES & BASAL LAMINA CHARACTERISTICS CAPILLARIESBASAL LAMINAEXAMPLES OF LOCATIONS CONTINUOUSCOMPLETEMUSCLE, TESTIS, BRAIN, THYMUS FENESTRATEDCOMPLETEGLOMERULUS, ADRENAL DISCONTINUOUSINCOMPLETE ORLIVER, SPLEEN, BONE OR SINUSOIDALLACKINGMARROW MUSCLEGLOMERULUSLIVER

25. Tongue, monkey 136

26. CONTINUOUS capillaries in muscle

27. Adrenal-cortex and medulla 186 FENESTRATED capillaries

28. Rib bone marrow 420 SINUSOIDAL capillaries

29. SINUSOIDAL capillaries 420

30. Gall bladder & liver, monkey 155 SINUSOIDAL capillaries

31. Bile duct with portal vein, monkey 126

32. Bile duct with portal vein, monkey 126

33. Vein of Spermatic cord 196

34. UT196 valves in large vein of spermatic cord 196

36. EM 10b

37. CARDIAC MUSCLE - DIAD

38. CARDIAC MUSCLE

39. Opened Interclated disc in cardiac cells of Heart, endocardium 226

40. UT196 valve in lymphatic vessel in spermatic cord 196 vein lymphatic vessels artery

41. Slide 201 Higher magnification of intestinal villus: 1.Lymphatic capillary 2.Blood capillary 3.Endothelial cell 4.Central lacteal 32409

42. Slide 201 Intestinal villus of duodenum 1.Brush border 2.Central lacteal 32409

43. 447

44. 196a lymphatic vessels in spermatic cord

45. LYMPH VESSELS FUNCTIONS RETURN PROTEIN, FLUID, AND BLOOD CELLS TRANSPORT SECRETIONS (HORMONES, ANTIBODIES) TRANSPORT FAT (NEUTRAL FAT)

46. Thoracic duct 128

47. Thoracic duct 128

48. SUMMARY CARDIOVASCULAR SYSTEM Vessels are structurally adapted to physical requirements and metabolic needs

49. SUMMARY CARDIOVASCULAR SYSTEM Vessels are structurally adapted to physical requirements and metabolic needs